LECTURE TWO

Antibiotics from bacteriophage - an old treatment undergoing a resurgence. Lecture covers the theory and practice of using phage for antimicrobial treatment

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Phage

© Jem Stach - Material intended solely for students enrolled @ Newcastle University - MSc Industrial and Commercial Biotechnology. jem.stach@newcastle.ac.uk

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Huys I, Pirnay J-P, Lavigne R, et al. Paving a regulatory pathway for phage therapy. EMBO Reports. 2013;14(11):951-954. doi:10.1038/embor.2013.163.

Liu J, Dehbi M, Moeck G, Arhin F, Bauda P, Bergeron D, Callejo M et al. Antimicrobial drug discovery through bacteriophage genomics. Nat Biotechnol. 2004 Feb;22(2):185-91. Epub 2004 Jan 11.

Schuch, R., Nelson, D., & Fischetti, V. A. A bacteriolytic agent that detects and kills Bacillus anthracis. Nature, 2002, 418(6900), 884-889

Stone, R. "Stalin's forgotten cure." Science 298.5594 (2002): 728-731.

Extra material associated with this lecture can be found in the Reading section