You have just carried out a BLAST search with a new protein.

The search has returned 100+ hits. If you look carefully at the hits, you will see that there are no exact matches.

Look at the graph (if you have used a system that does not produce a graph then look at the alignments). Notice anything?

You may have noticed a domain was indicated on the 'format' page at NCBI.

All the hits are the same region of the query protein (amino acids 85 - 220). Why?

Note the region of the hits (i.e. amino acids 85 - 220) and proceed to the ProSite and SMART searches.