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Antigen presenting cells

2010-11-25T18:44:14Z

090120998:

Antigen Presenting Cells (or APCs) are involved in the immune system and activation of [[T cells|T-cells]]. APCs cover several cell types including [[dendritic cell|dendritic cells]] and [[Macrophage|macrophages]]. 

 

== Dendritic cells ==

Dendritic cells have long projections away from the main cell body similar to the dendrites found on the nerve cell (hence the name). Thes cells begin as all cells in the immune system do, they are created by differentiation of [[pluripotent stem cell|pluripotent stem cells]] found in the [[bone marrow|bone marrow]]. Immature dendritic cells leave the bone marrow traveling in the blood stream into tissues, as they travel they perform [[macropinocytosis|macropinocytosis]] to take in large amounts of ECF. Dendritic cells do have the ability to digest pathogens they encounter but their main function in the immune system is to activate virgin T-cells by presenting any foriegen molecules that has been picked up on the cell's travels. This gives a vital link between the [[innate immune response|innate ]]and [[adaptive immune response|adaptive immune response]].

 

== Macrophages ==

Macrophages perform phagocytosis upon any invading molecule/cell that it recognises, the digested marticals are then presented on its cell surface to activate T-cells to destroy any more of the invader is present. Macrophages are mature cells that reside in most tissues, some tissues have specialised versions of macrophages, and in the limphoid organs. <ref>Murphy K, et al.;Janeway's Immunobiology; 7th ed; 2008</ref>

 

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Antigen presenting cells

2010-11-25T18:28:54Z

090120998: Created page with ' Antigen Presenting Cells (or APCs) are involved in the immune system and activation of T-cells. APCs cover several cell types including dendritic cells and macrophages.&nbs…'

Antigen Presenting Cells (or APCs) are involved in the immune system and activation of T-cells. APCs cover several cell types including dendritic cells and macrophages. 

 

== Dendritic cells ==

Dendritic cells have long projections away from the main cell body similar to the dendrites found on the nerve cell (hence the name). Thes cells begin as all cells in the immune system do, they are created by differentiation of pluripotent stem cells found in the bone marrow. Immature dendritic cells leave the bone marrow traveling in the blood stream into tissues, as they travel they perform macropinocytosis to take in large amounts of ECF. Dendritic cells do have the ability to digest pathogens they encounter but their main function in the immune system is to activate virgin T-cells by presenting any foriegen molecules that has been picked up on the cell's travels. This gives a vital link between the innate and adaptive immune response.

 

== Macrophages ==

Macrophages perform phagocytosis upon any invading molecule/cell that it recognises, the digested marticals are then presented on its cell surface to activate T-cells to destroy any more of the invader is present. Macrophages are mature cells that reside in most tissues, some tissues have specialised versions of macrophages, and in the limphoid organs. <ref>Murphy K, et al.;Janeway's Immunobiology; 7th ed; 2008</ref>

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Eukaryotic cells

2010-11-25T13:56:55Z

090120998: Created page with 'Eukaryotic cells are any cell with a membrane bound nucleus. The term 'Eukaryote' comes from the the greek meaning trully nuclear.<ref>http://library.thinkquest.org/C004535/eukar…'

Eukaryotic cells are any cell with a membrane bound nucleus. The term 'Eukaryote' comes from the the greek meaning trully nuclear.<ref>http://library.thinkquest.org/C004535/eukaryotic_cells.html ; Accessed on 24/11/2010</ref> Eukaryotes include animal and plant cells. these tend to be highly specialised for function within large multicellular organisms (eg. Mammals)