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Calcium 'Puffs'

2011-11-15T17:13:20Z

100674693: Created page with "Calcium 'Puffs' are a form of Calcium Signalling that results from elementary events within the cell. These events are localised in space and are short in ..."

Calcium 'Puffs' are a form of [[Calcium signalling|Calcium Signalling that]] results from elementary events within the cell. These events are localised in space and are short in duration, and result from Calcium release from a cluster of IP3R's in  the presence of IP3, ATP and Ca2+.

 

References

Alberts B., Johnson A., Lewis J., Raff M., Roberts K., Walkter P., (2008) Molecular Biology Of The Cell, 5th edition, Newy York: Garland Science

Category:Transcription Bubbles

2011-01-10T12:21:13Z

100674693:

During the elongation phase of RNA synthesis transcription is carried out by the formation of transcription bubbles. The elongation phase initiates once the first phosphodiester bond has formed. The loss of the sigma factor allows the core enzyme to bind strongly to the DNA template. The area containing RNA polymerase, DNA and the newly forming RNA forms the transcription bubble. This is a localised 'melting' of DNA that forms a bubble like structure in which DNA transcription occurs. The newly formed RNA forms a 'hybrid helix' with the DNA template strand. The transcription bubble moves rapidly along the DNA template and creates an elongation rate of '50 nucleotides per second'. The relative lengths of the DNA-RNA hybrid and the unwound DNA stays relatively constant throughout the movement of the transcription bubble indicates that DNA is unwound at the same rate as it is reformed<ref>Berg J., Tymoczko J and Stryer L. (2007) Biochemistry, 6th edition, New York: WH Freeman.</ref>. 

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Category:Transcription Bubbles

2011-01-10T12:20:51Z

100674693:

Category:Transcription Bubbles

2010-12-21T12:11:13Z

100674693: Created page with 'During the elongation phase of RNA synthesis transcription is carried out by the formation of transcription bubbles. The elongation phase initiates once the first phosphodiester …'

During the elongation phase of RNA synthesis transcription is carried out by the formation of transcription bubbles. The elongation phase initiates once the first phosphodiester bond has formed. The loss of the sigma factor allows the core enzyme to bind strongly to the DNA template. The area containing RNA polymerase, DNA and the newly forming RNA forms the transcription bubble. This is a localised 'melting' of DNA that forms a bubble like structure in which DNA transcription occurs. The newly formed RNA forms a 'hybrid helix' with the DNA template strand. The transcription bubble moves rapidly along the DNA template and creates an elongation rate of '50 nucleotides per second'. The relative lengths of the DNA-RNA hybrid and the unwound DNA stays relatively constant throughout the movement of the transcription bubble indicates that DNA is unwound at the same rate as it is reformed. (Berg, 2007: 828) 

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'''Reference''' 

'''Berg J., Tymoczko J and Stryer L. (2007) Biochemistry, 6th edition, New York: WH Freeman.'''

School of Biomedical Sciences Wiki

2010-12-17T13:26:15Z

100674693:

School of Biomedical Sciences Wiki

2010-12-17T13:25:18Z

100674693:

 [[Category:Transcription Bubbles]]

p828 

biochem book