https://teaching.ncl.ac.uk/bms/wiki//api.php?action=feedcontributions&feedformat=atom&user=130056410 2026-04-10T14:40:13Z User contributions MediaWiki 1.44.0 https://teaching.ncl.ac.uk/bms/wiki//index.php?title=NAPQI&diff=11234 2014-10-21T17:16:05Z

<p>130056410: Created page with &quot;&amp;nbsp;NAPQI (N-acetyl-p-benzoquinone imine) Is a very reactive biproduct of the metabolism of paracetamol via the P-450 system. It is toxic due to it binding to e...&quot;</p> <hr /> <div>&amp;nbsp;NAPQI (N-acetyl-p-benzoquinone imine) Is a very reactive biproduct of the metabolism of [[Paracetamol|paracetamol]] via the P-450 system. It is toxic due to it binding to essential protiens inside the hepatic cells causing liver damage.&amp;nbsp;<br /> <br /> It is produced when levels of [[Glutathione|glutathion]] in the liver cells are low.<br /> <br /> <br /> <br /> References:&amp;nbsp;<br /> <br /> http://www.vetmed.vt.edu/education/Curriculum/VM8304/vet%20pathology/CASES/CELLINJURY2/PAGE3-2.htm</div>

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