https://teaching.ncl.ac.uk/bms/wiki//api.php?action=feedcontributions&feedformat=atom&user=140412129The School of Biomedical Sciences Wiki - User contributions [en]2026-04-17T10:05:18ZUser contributionsMediaWiki 1.44.0https://teaching.ncl.ac.uk/bms/wiki//index.php?title=SRY_Gene&diff=12838SRY Gene2014-11-28T02:24:43Z<p>140412129: Created page with "&nbsp;Known as the Sex Determining Region Y, the SRY Gene is located on the Y chromosome at the cytogenic location: Yp11.3.<br> '''Function''' The SRY Gene induces male sex d..."</p>
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<div>&nbsp;Known as the Sex Determining Region Y, the SRY Gene is located on the Y chromosome at the cytogenic location: Yp11.3.<br> <br />
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'''Function''' <br />
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The SRY Gene induces male sex determination by producing a protein named the SRY protein. When activated, the SRY protein initiates the determination of unspecified cells into testes during embryonic development. This protein trigger produces a male phenotype and male hormones in mammals where the gene is active.<br><br> '''Health Conditions''' <br />
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Complications can arise with inheritence of the SRY Gene due to problems in mutations, insertions and deletions of the gene. Such inheritence patterns can lead to various health conditions such as: <br />
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*Swyers syndrome- caused by a mutation of the SRY Gene <br />
*46 XX- Due to the insertion of SRY into an X chromosome.<br />
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<br><br><br><br>http://www.nature.com/scitable/content/18935/pierce_4_10_large_2.jpg<br> <br />
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Sources: <br />
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*http://ghr.nlm.nih.gov/gene/SRY <br />
*http://embryo.asu.edu/pages/sex-determining-region-y-mammals <br />
*http://dev.biologists.org/content/137/23/3921.full.pdf</div>140412129https://teaching.ncl.ac.uk/bms/wiki//index.php?title=File:SRY.jpg&diff=12837File:SRY.jpg2014-11-28T02:23:06Z<p>140412129: SRY Gene on Y chromosome.</p>
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<div>SRY Gene on Y chromosome.</div>140412129