The School of Biomedical Sciences Wiki - User contributions [en]

Pleckstrin homology

2018-10-23T20:58:55Z

160306419: Created page with " A pleckstrin homology domain is the 11th most comain domain in the human proteome. At around 100 amino acids long the domain has a high affinity and high specificity for ph..."

 A pleckstrin homology domain is the 11th most comain domain in the human proteome. At around 100 amino acids long the domain has a high affinity and high specificity for phosphoinositides with about 10% of domains sharing this property. The exact function is unknown but they are thought to be components in the cells cytoskeleton or involved in intracellular signalling. 

https://www.ncbi.nlm.nih.gov/pubmed/17233582

Alpha-methylacyl-CoA racemase (AMACR)

2017-12-05T19:29:30Z

160306419:

Alpha-methylacyl-CoA racemase (AMACR) is an [[Enzyme]] which regulates the [[Metabolism]] of branched chain lipids which are essential in the human diet and are found in many drugs like ibroprofen. AMACR catalyses the [[Chiral]] inversion of many 2-methyl acids, and regulates the entry of branched-chain lipids into the peroxisomal and mitochondrial beta-oxidation pathways. [1]

[1] Lloyd MD. Department of Pharmacy & Pharmacology, Medicinal Chemistry, University of Bath, Claverton Down, Bath, UK.

Alpha-methylacyl-CoA racemase (AMACR)

2017-12-05T19:28:44Z

160306419:

Alpha-methylacyl-CoA racemase (AMACR) is an [[Enzyme]] which regulates the [[Metabolism]] of branched chain lipids which are essential in the human diet and are found in many drugs like ibroprofen. AMACR catalyses the [[Chiral]] inversion of many 2-methyl acids, and regulates the entry of branched-chain lipids into the peroxisomal and mitochondrial beta-oxidation pathways.

Lloyd MD. Department of Pharmacy & Pharmacology, Medicinal Chemistry, University of Bath, Claverton Down, Bath, UK

Alpha-methylacyl-CoA racemase (AMACR)

2017-12-05T19:26:33Z

160306419:

Alpha-methylacyl-CoA racemase (AMACR) is an [[Enzyme]] which regulates the [[Metabolism]] of branched chain lipids which are essential in the human diet and are found in many drugs like ibroprofen. AMACR catalyses the [[Chiral]] inversion of many 2-methyl acids, and regulates the entry of branched-chain lipids into the peroxisomal and mitochondrial beta-oxidation pathways. 

<ref name="Department of Pharmacy & Pharmacology, Medicinal Chemistry, University of Bath, Claverton Down, Bath, UK">Lloyd MD. Department of Pharmacy & Pharmacology, Medicinal Chemistry, University of Bath, Claverton Down, Bath, UK</ref>

Alpha-methylacyl-CoA racemase (AMACR)

2017-12-05T19:23:35Z

160306419: Created page with " Alpha-methylacyl-CoA racemase (AMACR) is an Enzyme which regulates the Metabolism of branched chain lipids which are essential in the human diet and are f..."

Alpha-methylacyl-CoA racemase (AMACR) is an [[Enzyme]] which regulates the [[Metabolism]] of branched chain lipids which are essential in the human diet and are found in many drugs like ibroprofen. AMACR catalyses the [[Chiral]] inversion of many 2-methyl acids, and regulates the entry of branched-chain lipids into the peroxisomal and mitochondrial beta-oxidation pathways. 

<ref name="Department of Pharmacy & Pharmacology, Medicinal Chemistry, University of Bath, Claverton Down, Bath, UK" />