https://teaching.ncl.ac.uk/bms/wiki//api.php?action=feedcontributions&feedformat=atom&user=160617809The School of Biomedical Sciences Wiki - User contributions [en]2026-04-15T05:42:30ZUser contributionsMediaWiki 1.44.0https://teaching.ncl.ac.uk/bms/wiki//index.php?title=Glucokinase&diff=15857Glucokinase2016-10-20T21:13:49Z<p>160617809: </p>
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<div>Glucokinase is an enzyme that phosphorylates glucose to become glucose-6-phosphate. It is an isozyme of hexokinase (hexokinase IV) that is present in hepatocytes. Compared to the other forms of hexokinase, glucokinase has a low affinity for glucose. This means that when glucose levels in the body are low, glucose isn't phosphorylated to become glucose-6-phosphate, and it goes to other tissues that have a greater need for the glucose. Furthermore, glucokinase is not inhibited by the product glucose-6-phosphate. This allows the enzyme to continually phosphorylate glucose, even when the concentration of glucose-6-phosphate is very high<ref>Lehninger, A. L. Nelson, D. L. Cox, M. M. (2000) Principles of Biochemistry, 6th edition, New York: Worth Publishers. Chapter 15, page 578.</ref>.&nbsp; <br />
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=== <span>References&nbsp;</span>&nbsp; ===<br />
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<references /></div>160617809https://teaching.ncl.ac.uk/bms/wiki//index.php?title=Glucokinase&diff=15856Glucokinase2016-10-20T21:13:34Z<p>160617809: Created page with "Glucokinase is an enzyme that phosphorylates glucose to become glucose-6-phosphate. It is an isozyme of hexokinase (hexokinase IV) that is present in hepatocytes. Compared to the..."</p>
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<div>Glucokinase is an enzyme that phosphorylates glucose to become glucose-6-phosphate. It is an isozyme of hexokinase (hexokinase IV) that is present in hepatocytes. Compared to the other forms of hexokinase, glucokinase has a low affinity for glucose. This means that when glucose levels in the body are low, glucose isn't phosphorylated to become glucose-6-phosphate, and it goes to other tissues that have a greater need for the glucose. Furthermore, glucokinase is not inhibited by the product glucose-6-phosphate. This allows the enzyme to continually phosphorylate glucose, even when the concentration of glucose-6-phosphate is very high<ref>Lehninger, A. L. Nelson, D. L. Cox, M. M. (2000) Principles of Biochemistry, 6th edition, New York: Worth Publishers. Chapter 15, page 578.</ref>.&nbsp; <br />
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=== <span>References&nbsp;</span>&nbsp; ===<br />
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