The School of Biomedical Sciences Wiki - User contributions [en]

Ascorbic acid

2016-12-04T14:11:54Z

170016630:

[[Image:Imagefly.png|border|right|250x250px|Fischer Projection of the Structure Ascorbic acid.png]]

 Ascorbic acid, also known as Vitamin C, is an [[Water|water]] soluble essential nutrient in [[Human|humans]] but not synthesised in the human body which therefore requires it to be obtained through dietary means. Its molecular formula is C6H8O6, with a molecular weight of 176.124 g/mol.<ref>Ascorbic acid | C6H8O6 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2016 [cited 4 December 2016]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/ascorbic_acid</ref>

It acts as an antioxidant, reducing agent and coenzyme in many metabolic pathways. One example is [[Collagen|collagen]] formation, where ascorbic acid is a cofactor of iron in the hydroxylation of the [[Amino acids|amino acids]] [[Proline|proline]] and [[Lysine|lysine]]. Deficiency of ascorbic acid will lead to scuvy or its related symptoms.<ref>Otten JJ, Hellwig JP, Meyers LD, eds; Dietary Reference Intakes: The Essential Guide to Nutrient Requirements, Washington, DC: The National Academies Press, 2006, p.203</ref><ref>NAS, Food and Nutrition Board, Institute of Medicine; Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. National Academy Press, Washington, D.C., pg. 96, 2000. Available from, as of 3 December 2016: http://www.nap.edu/catalog/9810.html</ref>

Ascorbic acid exists in [[Blood|blood]] [[Plasma|plasma]], [[Leukocytes|leukocytes]] and [[Tissue|tissues]], is absorbed in the [[Intestine|intestines]] and is excreted through the [[Kidney|renal]] pathway.<ref>Gilman, A.G., T.W. Rall, A.S. Nies and P. Taylor (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 8th ed. New York, NY. Pergamon Press, 1990., p. 1548</ref>

 

=== References ===

<references />

File:Imagefly.png

2016-12-04T14:05:24Z

170016630: Fischer Projection of the structure of Ascorbic acid

Fischer Projection of the structure of Ascorbic acid

Ascorbic acid

2016-12-04T13:58:07Z

170016630:

Ascorbic acid, also known as Vitamin C, is an [[Water|water]] soluble essential nutrient in [[Human|humans]] but not synthesised in the human body which therefore requires it to be obtained through dietary means. Its molecular formula is C6H8O6, with a molecular weight of 176.124 g/mol.<ref>Ascorbic acid | C6H8O6 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2016 [cited 4 December 2016]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/ascorbic_acid</ref>

It acts as an antioxidant, reducing agent and coenzyme in many metabolic pathways. One example is [[Collagen|collagen]] formation, where ascorbic acid is a cofactor of iron in the hydroxylation of the [[Amino acids|amino acids]] [[Proline|proline]] and [[Lysine|lysine]]. Deficiency of ascorbic acid will lead to scuvy or its related symptoms.<ref>Otten JJ, Hellwig JP, Meyers LD, eds; Dietary Reference Intakes: The Essential Guide to Nutrient Requirements, Washington, DC: The National Academies Press, 2006, p.203</ref><ref>NAS, Food and Nutrition Board, Institute of Medicine; Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. National Academy Press, Washington, D.C., pg. 96, 2000. Available from, as of 3 December 2016: http://www.nap.edu/catalog/9810.html</ref>

Ascorbic acid exists in [[Blood|blood]] [[Plasma|plasma]], [[Leukocytes|leukocytes]] and [[Tissue|tissues]], is absorbed in the [[Intestine|intestines]] and is excreted through the [[Kidney|renal]] pathway.<ref>Gilman, A.G., T.W. Rall, A.S. Nies and P. Taylor (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 8th ed. New York, NY. Pergamon Press, 1990., p. 1548</ref>

 

=== References ===

<references />

Ascorbic acid

2016-12-04T08:18:06Z

170016630: Created page with " Ascorbic acid, also known as Vitamin C, is an water soluble essential nutrient in humans but not synthesised in the human body which therefore requires it to be obtained th..."

Ascorbic acid, also known as Vitamin C, is an water soluble essential nutrient in humans but not synthesised in the human body which therefore requires it to be obtained through dietary means. Its molecular formula is C6H8O6, with a molecular weight of 176.124 g/mol.<ref>Ascorbic acid | C6H8O6 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2016 [cited 4 December 2016]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/ascorbic_acid</ref>

It acts as an antioxidant, reducing agent and coenzyme in many metabolic pathways. One example is collagen formation, where ascorbic acid is a cofactor of iron in the hydroxylation of the amino acids proline and lysine. Deficiency of ascorbic acid will lead to scuvy or its related symptoms.<ref>Otten JJ, Hellwig JP, Meyers LD, eds; Dietary Reference Intakes: The Essential Guide to Nutrient Requirements, Washington, DC: The National Academies Press, 2006, p.203</ref><ref>NAS, Food and Nutrition Board, Institute of Medicine; Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. National Academy Press, Washington, D.C., pg. 96, 2000. Available from, as of 3 December 2016: http://www.nap.edu/catalog/9810.html</ref>

Ascorbic acid exists in blood plasma, leukocytes and tissues, is absorbed in the intestines and is excreted through the renal pathway.<ref>Gilman, A.G., T.W. Rall, A.S. Nies and P. Taylor (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 8th ed. New York, NY. Pergamon Press, 1990., p. 1548</ref>

 

=== References ===

<references />