Acetyl cholinesterase

2018-11-23T02:11:24Z

180658390:

 Acetyl cholinesterase (AChE) is an enzyme with a catalytic function of hydrolysing the [[Neurotransmitter|neurotransmitter]] [[Acetylcholine|acetylcholine (Ach)]] into its two elements: choline and acetate. This reaction happens at the junctional fold in the [[Synaptic cleft|synaptic cleft]] where acetylcholine is exported out by the [[Secretory_vesicles|secretory vesicles]] from the [[Presynaptic knob|presynaptic knob]] and flow across the synapse. The acetylcholine interact and bind to the [[Postsynaptic receptor|postsynaptic receptor]] to transmit the signal.<ref>Daniel MQ. Acetylcholinesterase : Enzyme Structure, Reaction Dynamics, and Virtual Transition States. Chem. Rev., 1987, 87 (5), pp 955–979. This is available from DOI: 10.1021/cr00081a005.</ref> The removal of neurotransmitter after the [[Signal transmission|signal transmission]] at the [[Postsynaptic membrane|postsynaptic membrane]] is vital in order to enable the generation of new [[Action potential|action potential]] by [[Stimulus|stimulus]].

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Acetyl cholinesterase

2018-11-23T02:10:07Z

180658390: Created page with " Acetyl cholinesterase (AChE) is an enzyme with a catalytic function of hydrolysing the neurotransmitter acetylcholine (Ach) into its ..."

 Acetyl cholinesterase (AChE) is an enzyme with a catalytic function of hydrolysing the [[Neurotransmitter|neurotransmitter]] [[Acetylcholine|acetylcholine (Ach)]] into its two elements: choline and acetate. This reaction happens at the junctional fold in the [[Synaptic_cleft|synaptic cleft]] where acetylcholine is exported out by the [[Secretory_vesicle|secretory vesicle]] from the [[presynaptic knob|presynaptic knob]] and flow across the synapse. The acetylcholine interact and bind to the [[postsynaptic receptor|postsynaptic receptor]] to transmit the signal.<ref>Daniel MQ. Acetylcholinesterase : Enzyme Structure, Reaction Dynamics, and Virtual Transition States. Chem. Rev., 1987, 87 (5), pp 955–979. This is available from DOI: 10.1021/cr00081a005.</ref> The removal of neurotransmitter after the [[signal transmission|signal transmission]] at the [[Postsynaptic_membrane|postsynaptic membrane]] is vital in order to enable the generation of new [[Action_potential|action potential]] by [[Stimulus|stimulus]].

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Acetyl cholinesterase

Acetyl cholinesterase