View source for IgM

IgM stands for '[[Immunogobulin M|Immunogobulin M]]'. It is an antibody that is mainly concentrated in the [[Blood|blood]] and is the first to act in the primary [[Antibody|antibody]] response to a [[Pathogen|pathogen]]/[[Antigen|antigen]]&nbsp;<ref>Molecular Biology of the Cell, fifth edition, Alberts et al, Garland Science. pages 1553-1554</ref>. IgM binds tightly to anitgens containing multiple identical epitopes due to the presence of 10 combining sites. In proteins, [[Avidity]] describes the strength of multiple bonds whereas [[Affinity]] denotes the binding of a single site.<ref>Biochemistry - Berg, Stryer and Tymoczko 2011</ref> 

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