View source for Cosmid

&nbsp;Cosmids are a form of&nbsp;[[Plasmids|plasmids]] which can hold roughly double the amount of&nbsp;[[DNA|DNA]]&nbsp;that a regular plasmid can <ref>Berg, J.M., Tymoczko, J.L. and Stryer, L., 2012. Biochemistry. Seventh edition. New York: W.H. Freeman and Company.</ref> . A hybrid of bacterial plasmids and a [[Bacteriophage|bacteriophage]],&nbsp;the name 'cosmids' is derived from the [[Cos sites|''cos'' sites]],&nbsp;that they contain in their [[Lambda phage|Lambda phage]] region, which are crucial in the packaging process. The ''cos''&nbsp;sites also allow them to form what is known as cohesive ends, much like [[Sticky ends|sticky ends]], which allow the cosmid to [[Ligase|ligate]] back after foreign DNA is inserted into it. The functional uses of these cosmids is primarily for genetic manipulation, such as creating [[genomic library|genomic libraries]], therefore&nbsp;allowing us to [[DNA_Sequencing|sequence]] [[Organism|organism]]s.&nbsp;

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