Adrenegic receptor - Revision history

Nnjm2 at 15:18, 21 October 2015

2015-10-21T15:18:30Z

← Older revision		Revision as of 15:18, 21 October 2015
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	Adrenergic receptors respond to [[Adrenaline\|adrenaline]] and [[Noradrenaline\|noradrenaline]] and can be found in a variety of different tissues.		Adrenergic receptors respond to [[Adrenaline\|adrenaline]] and [[Noradrenaline\|noradrenaline]] and can be found in a variety of different tissues.

	Adrenergic receptors can be subdivided into two major classes: α- and β-adrenoreceptors.		Adrenergic receptors can be subdivided into two major classes: α- and β-adrenoreceptors.<br>



	~~For α-adrenoreceptors, the potency and affinity is noradrenaline ≥ adrenaline >> isoprenaline~~.<~~ref name="[1]">Whalen, K., Finkel, R. and Panavelil, T. (2015). Lippincott's Illustrated Reviews. Philadelphia, Pa.: Wolters Kluwer.</ref>~~

	For β-adrenoreceptors, the potency and affinity is isoprenaline > adrenaline > noradrenaline.<ref name="[1]">Whalen, K., Finkel, R. and Panavelil, T. (2015). Lippincott's Illustrated Reviews. Philadelphia, Pa.: Wolters Kluwer.</ref>

			For α-adrenoreceptors, the potency and affinity is noradrenaline ≥ adrenaline >> isoprenaline.<ref name="[1]">Whalen, K., Finkel, R. and Panavelil, T. (2015). Lippincott's Illustrated Reviews. Philadelphia, Pa.: Wolters Kluwer.</ref>

			For β-adrenoreceptors, the potency and affinity is isoprenaline > adrenaline > noradrenaline.<ref name="[1]">Whalen, K., Finkel, R. and Panavelil, T. (2015). Lippincott's Illustrated Reviews. Philadelphia, Pa.: Wolters Kluwer.</ref><br>

	α-Adrenoreceptors are subdivided into two subgroups, α<sub>1</sub> and α<sub>2</sub> receptors.		α-Adrenoreceptors are subdivided into two subgroups, α<sub>1</sub> and α<sub>2</sub> receptors.

	β-Adrenoreceptors are subdivided into two subgroups, β<sub>1</sub> and β<sub>2</sub> receptors.		β-Adrenoreceptors are subdivided into two subgroups, β<sub>1</sub> and β<sub>2</sub> receptors.<br>



	~~Effects mediated by adrenoreceptor (when activation):~~

	α<~~sub~~>~~1</sub>: Smooth muscle contraction, vasoconstriction~~

	~~α<sub>2</sub>: Causes feedback inhibition~~

	~~β<sub>1</sub>: Increase in the rate and force of contraction of the heart~~

	~~β<sub>2</sub>: Smooth muscle relaxation, bronchodilation~~

			Effects mediated by adrenoreceptor (when activation):

			*α<sub>1</sub>: Smooth muscle contraction, vasoconstriction
			*α<sub>2</sub>: Causes feedback inhibition
			*β<sub>1</sub>: Increase in the rate and force of contraction of the heart
			*β<sub>2</sub>: Smooth muscle relaxation, bronchodilation<br>

	Adrenergic receptors are [[G-protein Coupled Receptor\|G-protein coupled receptors]]. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>		Adrenergic receptors are [[G-protein Coupled Receptor\|G-protein coupled receptors]]. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>

150015075 at 14:01, 21 October 2015

2015-10-21T14:01:18Z

← Older revision		Revision as of 14:01, 21 October 2015
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	Adrenergic receptors can be subdivided into two major classes: α- and β-adrenoreceptors.		Adrenergic receptors can be subdivided into two major classes: α- and β-adrenoreceptors.

	For α-adrenoreceptors, the potency and affinity is noradrenaline ≥ adrenaline >> isoprenaline.<ref name="[1]">Whalen, K., Finkel, R. and Panavelil, T. (2015). Lippincott's Illustrated Reviews. Philadelphia, Pa.: Wolters Kluwer.</ref>

			For α-adrenoreceptors, the potency and affinity is noradrenaline ≥ adrenaline >> isoprenaline.<ref name="[1]">Whalen, K., Finkel, R. and Panavelil, T. (2015). Lippincott's Illustrated Reviews. Philadelphia, Pa.: Wolters Kluwer.</ref>

	For β-adrenoreceptors, the potency and affinity is isoprenaline > adrenaline > noradrenaline.<ref name="[1]">Whalen, K., Finkel, R. and Panavelil, T. (2015). Lippincott's Illustrated Reviews. Philadelphia, Pa.: Wolters Kluwer.</ref>		For β-adrenoreceptors, the potency and affinity is isoprenaline > adrenaline > noradrenaline.<ref name="[1]">Whalen, K., Finkel, R. and Panavelil, T. (2015). Lippincott's Illustrated Reviews. Philadelphia, Pa.: Wolters Kluwer.</ref>



	α-Adrenoreceptors are subdivided into two subgroups, α<sub>1</sub> and α<sub>2</sub> receptors.		α-Adrenoreceptors are subdivided into two subgroups, α<sub>1</sub> and α<sub>2</sub> receptors.

	β-Adrenoreceptors are subdivided into two subgroups, β<sub>1</sub> and β<sub>2</sub> receptors.		β-Adrenoreceptors are subdivided into two subgroups, β<sub>1</sub> and β<sub>2</sub> receptors.



			Effects mediated by adrenoreceptor (when activation):

			α<sub>1</sub>: Smooth muscle contraction, vasoconstriction

			α<sub>2</sub>: Causes feedback inhibition

			β<sub>1</sub>: Increase in the rate and force of contraction of the heart

			β<sub>2</sub>: Smooth muscle relaxation, bronchodilation



	Adrenergic receptors are [[G-protein Coupled Receptor\|G-protein coupled receptors]]. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>		Adrenergic receptors are [[G-protein Coupled Receptor\|G-protein coupled receptors]]. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>

150015075 at 07:24, 21 October 2015

2015-10-21T07:24:24Z

← Older revision		Revision as of 07:24, 21 October 2015
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	Adrenergic receptors respond to [[Adrenaline\|adrenaline]] and [[Noradrenaline\|noradrenaline]] and can be found in a variety of different tissues.		Adrenergic receptors respond to [[Adrenaline\|adrenaline]] and [[Noradrenaline\|noradrenaline]] and can be found in a variety of different tissues.

	Adrenergic receptors can be subdivided into two major classes: α- and β-adrenoreceptors.		Adrenergic receptors can be subdivided into two major classes: α- and β-adrenoreceptors.

	For α-adrenoreceptors, the potency and affinity is noradrenaline ≥ adrenaline >> isoprenaline.		For α-adrenoreceptors, the potency and affinity is noradrenaline ≥ adrenaline >> isoprenaline.<ref name="[1]">Whalen, K., Finkel, R. and Panavelil, T. (2015). Lippincott's Illustrated Reviews. Philadelphia, Pa.: Wolters Kluwer.</ref>

	For β-adrenoreceptors, the potency and affinity is isoprenaline > adrenaline > noradrenaline.		For β-adrenoreceptors, the potency and affinity is isoprenaline > adrenaline > noradrenaline.<ref name="[1]">Whalen, K., Finkel, R. and Panavelil, T. (2015). Lippincott's Illustrated Reviews. Philadelphia, Pa.: Wolters Kluwer.</ref>

	α-Adrenoreceptors are subdivided into two subgroups, α<sub>1</sub> and α<sub>2</sub> receptors.		α-Adrenoreceptors are subdivided into two subgroups, α<sub>1</sub> and α<sub>2</sub> receptors.

	β-Adrenoreceptors are subdivided into two subgroups, β<sub>1</sub> and β<sub>2</sub> receptors.		β-Adrenoreceptors are subdivided into two subgroups, β<sub>1</sub> and β<sub>2</sub> receptors.

	Adrenergic receptors are [[G-protein Coupled Receptor\|G-protein coupled receptors]]. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>		Adrenergic receptors are [[G-protein Coupled Receptor\|G-protein coupled receptors]]. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>

150015075 at 03:44, 21 October 2015

2015-10-21T03:44:41Z

← Older revision		Revision as of 03:44, 21 October 2015
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	Adrenergic receptors respond to [[Adrenaline\|adrenaline]] and [[Noradrenaline\|noradrenaline]] and can be found in a variety of different tissues.		Adrenergic receptors respond to [[Adrenaline\|adrenaline]] and [[Noradrenaline\|noradrenaline]] and can be found in a variety of different tissues.

	Adrenergic receptors can be ~~sub divided~~ into two major classes: α and β.		Adrenergic receptors can be subdivided into two major classes: α- and β-adrenoreceptors.

	~~Adrenergic~~ receptors ~~can be further subdived~~ into ~~α1 , α2~~, β1 and β2.		For α-adrenoreceptors, the potency and affinity is noradrenaline ≥ adrenaline >> isoprenaline.

			For β-adrenoreceptors, the potency and affinity is isoprenaline > adrenaline > noradrenaline.

			α-Adrenoreceptors are subdivided into two subgroups, α<sub>1</sub> and α<sub>2</sub> receptors.

			β-Adrenoreceptors are subdivided into two subgroups, β<sub>1</sub> and β<sub>2</sub> receptors.

	Adrenergic receptors are [[G-protein Coupled Receptor\|G-protein coupled receptors]]. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>		Adrenergic receptors are [[G-protein Coupled Receptor\|G-protein coupled receptors]]. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>

	=== References ===		=== References ===

	<references />		<references />

Nnjm2 at 16:12, 23 November 2011

2011-11-23T16:12:35Z

← Older revision		Revision as of 16:12, 23 November 2011
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	Adrenergic receptors can be further subdived into α1 , α2, β1 and β2.		Adrenergic receptors can be further subdived into α1 , α2, β1 and β2.

	Adrenergic receptors are [[G-~~protein_Coupled_Receptor~~\|G-protein coupled receptors]]. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>		Adrenergic receptors are [[G-protein Coupled Receptor\|G-protein coupled receptors]]. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>

	=== References~~<br>~~ ===		=== References ===

	~~ ~~<references />		<references />

Nnjm2 at 16:12, 23 November 2011

2011-11-23T16:12:21Z

← Older revision		Revision as of 16:12, 23 November 2011
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	Adrenergic receptors can be further subdived into α1 , α2, β1 and β2.		Adrenergic receptors can be further subdived into α1 , α2, β1 and β2.

	Adrenergic receptors are G-protein coupled receptors. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>		Adrenergic receptors are [[G-protein_Coupled_Receptor\|G-protein coupled receptors]]. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>

	=== References<br> ===		=== References<br> ===

	<references />		<references />

102125283 at 15:50, 23 November 2011

2011-11-23T15:50:40Z

← Older revision		Revision as of 15:50, 23 November 2011
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	Adrenergic receptors can be sub divided into two major classes: α and β.		Adrenergic receptors can be sub divided into two major classes: α and β.

	Adrenergic receptors can be further subdived into α1 , α2, β1 and β2.		Adrenergic receptors can be further subdived into α1 , α2, β1 and β2.

	Adrenergic receptors are G-protein coupled receptors. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>		Adrenergic receptors are G-protein coupled receptors. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>

102125283 at 15:50, 23 November 2011

2011-11-23T15:50:18Z

← Older revision		Revision as of 15:50, 23 November 2011
Line 3:		Line 3:
	Adrenergic receptors can be sub divided into two major classes: α and β.		Adrenergic receptors can be sub divided into two major classes: α and β.

	Adrenergic receptors can be further subdived into α1 , α2, β1 and β2.		Adrenergic receptors can be further subdived into α1 , α2, β1 and β2.

	Adrenergic receptors are G-protein coupled receptors. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>		Adrenergic receptors are G-protein coupled receptors. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>

102125283 at 15:50, 23 November 2011

2011-11-23T15:50:03Z

← Older revision		Revision as of 15:50, 23 November 2011
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	~~<references />~~
	Adrenergic receptors respond to [[Adrenaline\|adrenaline]] and [[Noradrenaline\|noradrenaline]] and can be found in a variety of different tissues.		Adrenergic receptors respond to [[Adrenaline\|adrenaline]] and [[Noradrenaline\|noradrenaline]] and can be found in a variety of different tissues.

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	Adrenergic receptors are G-protein coupled receptors. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>		Adrenergic receptors are G-protein coupled receptors. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>

	<br>		=== References<br> ===

			<references />

102125283 at 15:42, 23 November 2011

2011-11-23T15:42:08Z

← Older revision		Revision as of 15:42, 23 November 2011
Line 1:		Line 1:
			<references />
	Adrenergic receptors respond to [[Adrenaline\|adrenaline]] and [[Noradrenaline\|noradrenaline]] and can be found in a variety of different tissues.		Adrenergic receptors respond to [[Adrenaline\|adrenaline]] and [[Noradrenaline\|noradrenaline]] and can be found in a variety of different tissues.

Line 5:		Line 6:
	Adrenergic receptors can be further subdived into α1 , α2, β1 and β2.		Adrenergic receptors can be further subdived into α1 , α2, β1 and β2.

	Adrenergic receptors are G-protein coupled receptors. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>		Adrenergic receptors are G-protein coupled receptors. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>


			<br>