Ascorbic acid - Revision history

Nnjm2: Cleaned up layout and added some links.

2016-12-04T14:37:35Z

Cleaned up layout and added some links.

← Older revision		Revision as of 14:37, 4 December 2016
Line 1:		Line 1:
	[[Image:Imagefly.png\|border\|right\|250x250px\|Fischer Projection of the Structure Ascorbic acid.png]]		[[Image:Imagefly.png\|border\|right\|250x250px\|Fischer Projection of the Structure Ascorbic acid.png]]

	~~ ~~Ascorbic acid, also known as Vitamin C, is an [[Water\|water]] soluble essential nutrient in [[Human\|humans]] but not synthesised in the human body which therefore requires it to be obtained through dietary means. Its molecular formula is C<sub>6</sub>H<sub>8</sub><span style="font-size: 13.28px;">O</span><sub>6,</sub> with a molecular weight of 176.124 g/mol.<ref>Ascorbic acid \| C6H8O6 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2016 [cited 4 December 2016]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/ascorbic_acid</ref><sub></sub>		Ascorbic acid, also known as Vitamin C, is an [[Water\|water]] soluble essential nutrient in [[Human\|humans]] but not synthesised in the human body which therefore requires it to be obtained through dietary means. Its molecular formula is C<sub>6</sub>H<sub>8</sub><span style="font-size: 13.28px;">O</span><sub>6,</sub> with a molecular weight of 176.124 g/mol<ref>Ascorbic acid \| C6H8O6 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2016 [cited 4 December 2016]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/ascorbic_acid</ref>.<sub></sub>

	It acts as an antioxidant, reducing agent and coenzyme in many metabolic pathways. One example is [[Collagen\|collagen]] formation, where ascorbic acid is a cofactor of iron in the hydroxylation of the [[Amino acids\|amino acids]] [[Proline\|proline]] and [[Lysine\|lysine]]. Deficiency of ascorbic acid will lead to scuvy or its related symptoms.<ref>Otten JJ, Hellwig JP, Meyers LD, eds; Dietary Reference Intakes: The Essential Guide to Nutrient Requirements, Washington, DC: The National Academies Press, 2006, p.203</ref><ref>NAS, Food and Nutrition Board, Institute of Medicine; Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. National Academy Press, Washington, D.C., pg. 96, 2000. Available from, as of 3 December 2016: http://www.nap.edu/catalog/9810.html</ref>		It acts as an [[antioxidant\|antioxidant]], [[reducing agent\|reducing agent]] and [[coenzyme\|coenzyme]] in many [[metabolic pathways\|metabolic pathways]]. One example is [[Collagen\|collagen]] formation, where ascorbic acid is a cofactor of iron in the [[hydroxylation\|hydroxylation]] of the [[Amino acids\|amino acids]] [[Proline\|proline]] and [[Lysine\|lysine]]. Deficiency of ascorbic acid will lead to [[scuvy\|scuvy]] or its related symptoms<ref>Otten JJ, Hellwig JP, Meyers LD, eds; Dietary Reference Intakes: The Essential Guide to Nutrient Requirements, Washington, DC: The National Academies Press, 2006, p.203</ref><ref>NAS, Food and Nutrition Board, Institute of Medicine; Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. National Academy Press, Washington, D.C., pg. 96, 2000. Available from, as of 3 December 2016: http://www.nap.edu/catalog/9810.html</ref>.

	Ascorbic acid exists in [[Blood\|blood]] [[Plasma\|plasma]], [[Leukocytes\|leukocytes]] and [[Tissue\|tissues]], is absorbed in the [[Intestine\|intestines]] and is excreted through the [[Kidney\|renal]] pathway.<ref>Gilman, A.G., T.W. Rall, A.S. Nies and P. Taylor (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 8th ed. New York, NY. Pergamon Press, 1990., p. 1548</ref>		Ascorbic acid exists in [[Blood\|blood]] [[Plasma\|plasma]], [[Leukocytes\|leukocytes]] and [[Tissue\|tissues]], is absorbed in the [[Intestine\|intestines]] and is excreted through the [[Kidney\|renal]] pathway<ref>Gilman, A.G., T.W. Rall, A.S. Nies and P. Taylor (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 8th ed. New York, NY. Pergamon Press, 1990., p. 1548</ref>.

	~~<br>~~

	=== References ===		=== References ===

170016630 at 14:11, 4 December 2016

2016-12-04T14:11:54Z

← Older revision		Revision as of 14:11, 4 December 2016
Line 1:		Line 1:
			[[Image:Imagefly.png\|border\|right\|250x250px\|Fischer Projection of the Structure Ascorbic acid.png]]

	Ascorbic acid, also known as Vitamin C, is an [[Water\|water]] soluble essential nutrient in [[Human\|humans]] but not synthesised in the human body which therefore requires it to be obtained through dietary means. Its molecular formula is C<sub>6</sub>H<sub>8</sub><span style="font-size: 13.28px;">O</span><sub>6,</sub> with a molecular weight of 176.124 g/mol.<ref>Ascorbic acid \| C6H8O6 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2016 [cited 4 December 2016]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/ascorbic_acid</ref><sub></sub>		Ascorbic acid, also known as Vitamin C, is an [[Water\|water]] soluble essential nutrient in [[Human\|humans]] but not synthesised in the human body which therefore requires it to be obtained through dietary means. Its molecular formula is C<sub>6</sub>H<sub>8</sub><span style="font-size: 13.28px;">O</span><sub>6,</sub> with a molecular weight of 176.124 g/mol.<ref>Ascorbic acid \| C6H8O6 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2016 [cited 4 December 2016]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/ascorbic_acid</ref><sub></sub>

170016630 at 13:58, 4 December 2016

2016-12-04T13:58:07Z

← Older revision		Revision as of 13:58, 4 December 2016
Line 1:		Line 1:
	Ascorbic acid, also known as Vitamin C, is an water soluble essential nutrient in humans but not synthesised in the human body which therefore requires it to be obtained through dietary means. Its molecular formula is C<sub>6</sub>H<sub>8</sub><span style="font-size: 13.28px;">O</span><sub>6,</sub> with a molecular weight of 176.124 g/mol.<ref>Ascorbic acid \| C6H8O6 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2016 [cited 4 December 2016]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/ascorbic_acid</ref><sub></sub>		Ascorbic acid, also known as Vitamin C, is an [[Water\|water]] soluble essential nutrient in [[Human\|humans]] but not synthesised in the human body which therefore requires it to be obtained through dietary means. Its molecular formula is C<sub>6</sub>H<sub>8</sub><span style="font-size: 13.28px;">O</span><sub>6,</sub> with a molecular weight of 176.124 g/mol.<ref>Ascorbic acid \| C6H8O6 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2016 [cited 4 December 2016]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/ascorbic_acid</ref><sub></sub>

	It acts as an antioxidant, reducing agent and coenzyme in many metabolic pathways. One example is collagen formation, where ascorbic acid is a cofactor of iron in the hydroxylation of the amino acids proline and lysine. Deficiency of ascorbic acid will lead to scuvy or its related symptoms.<ref>Otten JJ, Hellwig JP, Meyers LD, eds; Dietary Reference Intakes: The Essential Guide to Nutrient Requirements, Washington, DC: The National Academies Press, 2006, p.203</ref><ref>NAS, Food and Nutrition Board, Institute of Medicine; Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. National Academy Press, Washington, D.C., pg. 96, 2000. Available from, as of 3 December 2016: http://www.nap.edu/catalog/9810.html</ref>		It acts as an antioxidant, reducing agent and coenzyme in many metabolic pathways. One example is [[Collagen\|collagen]] formation, where ascorbic acid is a cofactor of iron in the hydroxylation of the [[Amino acids\|amino acids]] [[Proline\|proline]] and [[Lysine\|lysine]]. Deficiency of ascorbic acid will lead to scuvy or its related symptoms.<ref>Otten JJ, Hellwig JP, Meyers LD, eds; Dietary Reference Intakes: The Essential Guide to Nutrient Requirements, Washington, DC: The National Academies Press, 2006, p.203</ref><ref>NAS, Food and Nutrition Board, Institute of Medicine; Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. National Academy Press, Washington, D.C., pg. 96, 2000. Available from, as of 3 December 2016: http://www.nap.edu/catalog/9810.html</ref>

	Ascorbic acid exists in blood plasma, leukocytes and tissues, is absorbed in the intestines and is excreted through the renal pathway.<ref>Gilman, A.G., T.W. Rall, A.S. Nies and P. Taylor (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 8th ed. New York, NY. Pergamon Press, 1990., p. 1548</ref>		Ascorbic acid exists in [[Blood\|blood]] [[Plasma\|plasma]], [[Leukocytes\|leukocytes]] and [[Tissue\|tissues]], is absorbed in the [[Intestine\|intestines]] and is excreted through the [[Kidney\|renal]] pathway.<ref>Gilman, A.G., T.W. Rall, A.S. Nies and P. Taylor (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 8th ed. New York, NY. Pergamon Press, 1990., p. 1548</ref>

	<br>		<br>

170016630: Created page with " Ascorbic acid, also known as Vitamin C, is an water soluble essential nutrient in humans but not synthesised in the human body which therefore requires it to be obtained th..."

2016-12-04T08:18:06Z

Created page with " Ascorbic acid, also known as Vitamin C, is an water soluble essential nutrient in humans but not synthesised in the human body which therefore requires it to be obtained th..."

New page

Ascorbic acid, also known as Vitamin C, is an water soluble essential nutrient in humans but not synthesised in the human body which therefore requires it to be obtained through dietary means. Its molecular formula is C6H8O6, with a molecular weight of 176.124 g/mol.<ref>Ascorbic acid | C6H8O6 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2016 [cited 4 December 2016]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/ascorbic_acid</ref>

It acts as an antioxidant, reducing agent and coenzyme in many metabolic pathways. One example is collagen formation, where ascorbic acid is a cofactor of iron in the hydroxylation of the amino acids proline and lysine. Deficiency of ascorbic acid will lead to scuvy or its related symptoms.<ref>Otten JJ, Hellwig JP, Meyers LD, eds; Dietary Reference Intakes: The Essential Guide to Nutrient Requirements, Washington, DC: The National Academies Press, 2006, p.203</ref><ref>NAS, Food and Nutrition Board, Institute of Medicine; Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. National Academy Press, Washington, D.C., pg. 96, 2000. Available from, as of 3 December 2016: http://www.nap.edu/catalog/9810.html</ref>

Ascorbic acid exists in blood plasma, leukocytes and tissues, is absorbed in the intestines and is excreted through the renal pathway.<ref>Gilman, A.G., T.W. Rall, A.S. Nies and P. Taylor (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 8th ed. New York, NY. Pergamon Press, 1990., p. 1548</ref>

 

=== References ===

<references />

← Older revision		Revision as of 14:37, 4 December 2016
Line 1:		Line 1:
	[[Image:Imagefly.png\|border\|right\|250x250px\|Fischer Projection of the Structure Ascorbic acid.png]]		[[Image:Imagefly.png\|border\|right\|250x250px\|Fischer Projection of the Structure Ascorbic acid.png]]

	~~ ~~Ascorbic acid, also known as Vitamin C, is an [[Water\|water]] soluble essential nutrient in [[Human\|humans]] but not synthesised in the human body which therefore requires it to be obtained through dietary means. Its molecular formula is C<sub>6</sub>H<sub>8</sub><span style="font-size: 13.28px;">O</span><sub>6,</sub> with a molecular weight of 176.124 g/mol.<ref>Ascorbic acid \| C6H8O6 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2016 [cited 4 December 2016]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/ascorbic_acid</ref><sub></sub>		Ascorbic acid, also known as Vitamin C, is an [[Water\|water]] soluble essential nutrient in [[Human\|humans]] but not synthesised in the human body which therefore requires it to be obtained through dietary means. Its molecular formula is C<sub>6</sub>H<sub>8</sub><span style="font-size: 13.28px;">O</span><sub>6,</sub> with a molecular weight of 176.124 g/mol<ref>Ascorbic acid \| C6H8O6 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2016 [cited 4 December 2016]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/ascorbic_acid</ref>.<sub></sub>

	It acts as an antioxidant, reducing agent and coenzyme in many metabolic pathways. One example is [[Collagen\|collagen]] formation, where ascorbic acid is a cofactor of iron in the hydroxylation of the [[Amino acids\|amino acids]] [[Proline\|proline]] and [[Lysine\|lysine]]. Deficiency of ascorbic acid will lead to scuvy or its related symptoms.<ref>Otten JJ, Hellwig JP, Meyers LD, eds; Dietary Reference Intakes: The Essential Guide to Nutrient Requirements, Washington, DC: The National Academies Press, 2006, p.203</ref><ref>NAS, Food and Nutrition Board, Institute of Medicine; Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. National Academy Press, Washington, D.C., pg. 96, 2000. Available from, as of 3 December 2016: http://www.nap.edu/catalog/9810.html</ref>		It acts as an [[antioxidant\|antioxidant]], [[reducing agent\|reducing agent]] and [[coenzyme\|coenzyme]] in many [[metabolic pathways\|metabolic pathways]]. One example is [[Collagen\|collagen]] formation, where ascorbic acid is a cofactor of iron in the [[hydroxylation\|hydroxylation]] of the [[Amino acids\|amino acids]] [[Proline\|proline]] and [[Lysine\|lysine]]. Deficiency of ascorbic acid will lead to [[scuvy\|scuvy]] or its related symptoms<ref>Otten JJ, Hellwig JP, Meyers LD, eds; Dietary Reference Intakes: The Essential Guide to Nutrient Requirements, Washington, DC: The National Academies Press, 2006, p.203</ref><ref>NAS, Food and Nutrition Board, Institute of Medicine; Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. National Academy Press, Washington, D.C., pg. 96, 2000. Available from, as of 3 December 2016: http://www.nap.edu/catalog/9810.html</ref>.

	Ascorbic acid exists in [[Blood\|blood]] [[Plasma\|plasma]], [[Leukocytes\|leukocytes]] and [[Tissue\|tissues]], is absorbed in the [[Intestine\|intestines]] and is excreted through the [[Kidney\|renal]] pathway.<ref>Gilman, A.G., T.W. Rall, A.S. Nies and P. Taylor (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 8th ed. New York, NY. Pergamon Press, 1990., p. 1548</ref>		Ascorbic acid exists in [[Blood\|blood]] [[Plasma\|plasma]], [[Leukocytes\|leukocytes]] and [[Tissue\|tissues]], is absorbed in the [[Intestine\|intestines]] and is excreted through the [[Kidney\|renal]] pathway<ref>Gilman, A.G., T.W. Rall, A.S. Nies and P. Taylor (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 8th ed. New York, NY. Pergamon Press, 1990., p. 1548</ref>.

	~~<br>~~

	=== References ===		=== References ===