Category:Transcription Bubbles - Revision history

100674693 at 12:21, 10 January 2011

2011-01-10T12:21:13Z

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	'''<u>Reference</u>'''<br>		'''<u>Reference</u>'''<br>

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	'''<u>~~Berg J., Tymoczko J and Stryer L. (2007) Biochemistry, 6th edition, New York: WH Freeman.~~</u>'''~~<br>~~		'''<u><br></u>'''

100674693 at 12:20, 10 January 2011

2011-01-10T12:20:51Z

← Older revision		Revision as of 12:20, 10 January 2011
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	During the elongation phase of RNA synthesis transcription is carried out by the formation of transcription bubbles. The elongation phase initiates once the first phosphodiester bond has formed. The loss of the sigma factor allows the core enzyme to bind strongly to the DNA template. The area containing RNA polymerase, DNA and the newly forming RNA forms the transcription bubble. This is a localised 'melting' of DNA that forms a bubble like structure in which DNA transcription occurs. The newly formed RNA forms a 'hybrid helix' with the DNA template strand. The transcription bubble moves rapidly along the DNA template and creates an elongation rate of '50 nucleotides per second'. The relative lengths of the DNA-RNA hybrid and the unwound DNA stays relatively constant throughout the movement of the transcription bubble indicates that DNA is unwound at the same rate as it is reformed. (~~Berg~~, ~~2007~~: ~~828)~~<br>		During the elongation phase of RNA synthesis transcription is carried out by the formation of transcription bubbles. The elongation phase initiates once the first phosphodiester bond has formed. The loss of the sigma factor allows the core enzyme to bind strongly to the DNA template. The area containing RNA polymerase, DNA and the newly forming RNA forms the transcription bubble. This is a localised 'melting' of DNA that forms a bubble like structure in which DNA transcription occurs. The newly formed RNA forms a 'hybrid helix' with the DNA template strand. The transcription bubble moves rapidly along the DNA template and creates an elongation rate of '50 nucleotides per second'. The relative lengths of the DNA-RNA hybrid and the unwound DNA stays relatively constant throughout the movement of the transcription bubble indicates that DNA is unwound at the same rate as it is reformed<ref>Berg J., Tymoczko J and Stryer L. (2007) Biochemistry, 6th edition, New York: WH Freeman.</ref>.<br>

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	'''<u>Reference</u>'''<br>		'''<u>Reference</u>'''<br>

			'''<u></u>'''<references />

	'''<u>Berg J., Tymoczko J and Stryer L. (2007) Biochemistry, 6th edition, New York: WH Freeman.</u>'''<br>		'''<u>Berg J., Tymoczko J and Stryer L. (2007) Biochemistry, 6th edition, New York: WH Freeman.</u>'''<br>

100674693: Created page with 'During the elongation phase of RNA synthesis transcription is carried out by the formation of transcription bubbles. The elongation phase initiates once the first phosphodiester …'

2010-12-21T12:11:13Z

Created page with 'During the elongation phase of RNA synthesis transcription is carried out by the formation of transcription bubbles. The elongation phase initiates once the first phosphodiester …'

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During the elongation phase of RNA synthesis transcription is carried out by the formation of transcription bubbles. The elongation phase initiates once the first phosphodiester bond has formed. The loss of the sigma factor allows the core enzyme to bind strongly to the DNA template. The area containing RNA polymerase, DNA and the newly forming RNA forms the transcription bubble. This is a localised 'melting' of DNA that forms a bubble like structure in which DNA transcription occurs. The newly formed RNA forms a 'hybrid helix' with the DNA template strand. The transcription bubble moves rapidly along the DNA template and creates an elongation rate of '50 nucleotides per second'. The relative lengths of the DNA-RNA hybrid and the unwound DNA stays relatively constant throughout the movement of the transcription bubble indicates that DNA is unwound at the same rate as it is reformed. (Berg, 2007: 828) 

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'''Reference''' 

'''Berg J., Tymoczko J and Stryer L. (2007) Biochemistry, 6th edition, New York: WH Freeman.'''