Clotting factors - Revision history

180199620: Grammar

2018-11-16T17:53:16Z

Grammar

← Older revision		Revision as of 17:53, 16 November 2018
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	Blood coagulation is the transformation of [[Blood\|blood]] as a liquid into a solid gel-like blood "clot". A clot is formed when [[Platelets\|platelets]] stick to [[Collagen\|collagen]] exposed by a disrupted blood vessel lining. Other platelets then bind to the initial platelets to form what is called a [[Platelet plug\|platelet plug]]. The platelet plug is limited to the disrupted area and does not spread to the normal unaffected tissue. Clotting occurs on top of the platelet plug when [[Fibrinogen\|Fibrinogen]] (a large soluble [[Protein]]) is converted into [[Fibrin monomers\|Fibrin monomers]] (an insoluble thread-like molecule) by [[Thrombin\|thrombin]]. Fibrin monomers are then crosslinked into Fibrin polymers in the presence of [[Factor XIIIa\|factor XIIIa]] and [[Calcium\|Ca<sup>2+</sup>]]<ref>Factor XIIIa [Internet]. Pathologyoutlines.com. 2017 [cited 3 December 2017]. Available from: http://pathologyoutlines.com/topic/stainsfactorxiiia.html</ref>.		Blood coagulation is the transformation of [[Blood\|blood]] from a liquid into a solid gel-like blood "clot". A clot is formed when [[Platelets\|platelets]] stick to [[Collagen\|collagen]] exposed by a disrupted blood vessel lining. Other platelets then bind to the initial platelets to form what is called a [[Platelet plug\|platelet plug]]. The platelet plug is limited to the disrupted area and does not spread to the normal unaffected tissue. Clotting occurs on top of the platelet plug when [[Fibrinogen\|Fibrinogen]] (a large soluble [[Protein]]) is converted into [[Fibrin monomers\|Fibrin monomers]] (an insoluble thread-like molecule) by [[Thrombin\|thrombin]]. Fibrin monomers are then crosslinked into Fibrin polymers in the presence of [[Factor XIIIa\|factor XIIIa]] and [[Calcium\|Ca<sup>2+</sup>]]<ref>Factor XIIIa [Internet]. Pathologyoutlines.com. 2017 [cited 3 December 2017]. Available from: http://pathologyoutlines.com/topic/stainsfactorxiiia.html</ref>.

	=== References ===		=== References ===

	<references />		<references />

Nnjm2: Added the references correctly, that is, I added them as explained in the lecture.

2017-12-04T19:52:48Z

Added the references correctly, that is, I added them as explained in the lecture.

← Older revision		Revision as of 19:52, 4 December 2017
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	Blood coagulation is the transformation of [[Blood\|blood]] as a liquid into a solid gel-like blood "clot". A clot is formed when [[Platelets\|platelets]] stick to [[Collagen\|collagen]] exposed by a disrupted blood vessel lining. Other platelets then bind to the initial platelets to form what is called a [[Platelet plug\|platelet plug]]. The platelet plug is limited to the disrupted area and does not spread to the normal unaffected tissue. Clotting occurs on top of the platelet plug when [[Fibrinogen\|Fibrinogen]] (a large soluble [[Protein]]) is converted into [[Fibrin monomers\|Fibrin monomers]] (an insoluble thread-like molecule) by [[Thrombin\|thrombin]]. Fibrin monomers are then crosslinked into Fibrin polymers in the presence of [[Factor XIIIa\|factor XIIIa]] and [[Calcium\|Ca<sup>2+</sup>]]~~. ~~<ref>Factor XIIIa [Internet]. Pathologyoutlines.com. 2017 [cited 3 December 2017]. Available from: http://pathologyoutlines.com/topic/stainsfactorxiiia.html</ref>~~<br><br>~~<references />		Blood coagulation is the transformation of [[Blood\|blood]] as a liquid into a solid gel-like blood "clot". A clot is formed when [[Platelets\|platelets]] stick to [[Collagen\|collagen]] exposed by a disrupted blood vessel lining. Other platelets then bind to the initial platelets to form what is called a [[Platelet plug\|platelet plug]]. The platelet plug is limited to the disrupted area and does not spread to the normal unaffected tissue. Clotting occurs on top of the platelet plug when [[Fibrinogen\|Fibrinogen]] (a large soluble [[Protein]]) is converted into [[Fibrin monomers\|Fibrin monomers]] (an insoluble thread-like molecule) by [[Thrombin\|thrombin]]. Fibrin monomers are then crosslinked into Fibrin polymers in the presence of [[Factor XIIIa\|factor XIIIa]] and [[Calcium\|Ca<sup>2+</sup>]]<ref>Factor XIIIa [Internet]. Pathologyoutlines.com. 2017 [cited 3 December 2017]. Available from: http://pathologyoutlines.com/topic/stainsfactorxiiia.html</ref>.

			=== References ===

			<references />

160446287: Reference added

2017-12-03T15:13:27Z

Reference added

← Older revision		Revision as of 15:13, 3 December 2017
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	Blood coagulation is the transformation of [[Blood\|blood]] as a liquid into a solid gel-like blood "clot". A clot is formed when [[Platelets\|platelets]] stick to [[Collagen\|collagen]] exposed by a disrupted blood vessel lining. Other platelets then bind to the initial platelets to form what is called a [[Platelet plug\|platelet plug]]. The platelet plug is limited to the disrupted area and does not spread to the normal unaffected tissue. Clotting occurs on top of the platelet plug when [[Fibrinogen\|Fibrinogen]] (a large soluble [[Protein]]) is converted into [[Fibrin monomers\|Fibrin monomers]] (an insoluble thread-like molecule) by [[Thrombin\|thrombin]]. Fibrin monomers are then crosslinked into Fibrin polymers in the presence of [[Factor XIIIa\|factor XIIIa]] and [[Calcium\|Ca<sup>2+</sup>]].		Blood coagulation is the transformation of [[Blood\|blood]] as a liquid into a solid gel-like blood "clot". A clot is formed when [[Platelets\|platelets]] stick to [[Collagen\|collagen]] exposed by a disrupted blood vessel lining. Other platelets then bind to the initial platelets to form what is called a [[Platelet plug\|platelet plug]]. The platelet plug is limited to the disrupted area and does not spread to the normal unaffected tissue. Clotting occurs on top of the platelet plug when [[Fibrinogen\|Fibrinogen]] (a large soluble [[Protein]]) is converted into [[Fibrin monomers\|Fibrin monomers]] (an insoluble thread-like molecule) by [[Thrombin\|thrombin]]. Fibrin monomers are then crosslinked into Fibrin polymers in the presence of [[Factor XIIIa\|factor XIIIa]] and [[Calcium\|Ca<sup>2+</sup>]]. <ref>Factor XIIIa [Internet]. Pathologyoutlines.com. 2017 [cited 3 December 2017]. Available from: http://pathologyoutlines.com/topic/stainsfactorxiiia.html</ref><br><br><references />

Nnjm2: Cleaned up the text. Page needs some refs.

2017-11-25T09:00:50Z

Cleaned up the text. Page needs some refs.

← Older revision		Revision as of 09:00, 25 November 2017
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	Blood coagulation is the transformation of [[Blood\|blood]] as a liquid into a solid gel like blood "clot". A clot is formed when [[~~platelets~~\|platelets]] stick to [[Collagen\|collagen]] exposed by~~ ~~a disrupted blood vessel lining. Other platelets then bind to the initial platelets to form what is called a [[~~platelet~~ plug\|platelet plug]]. The platelet plug is limited to the disrupted area and does not spread to the normal unaffected tissue. Clotting occurs on top of the platelet plug when~~ ~~[[Fibrinogen\|Fibrinogen]] (a large soluble [[Protein]]) is converted into [[Fibrin monomers\|Fibrin monomers]] (an insoluble thread like molecule)~~ ~~by [[Thrombin\|thrombin]]. Fibrin monomers are then~~ ~~crosslinked into Fibrin polymers in the presence of [[Factor XIIIa\|factor XIIIa]] and [[Calcium\|Ca<sup>2+</sup>]].		Blood coagulation is the transformation of [[Blood\|blood]] as a liquid into a solid gel-like blood "clot". A clot is formed when [[Platelets\|platelets]] stick to [[Collagen\|collagen]] exposed by a disrupted blood vessel lining. Other platelets then bind to the initial platelets to form what is called a [[Platelet plug\|platelet plug]]. The platelet plug is limited to the disrupted area and does not spread to the normal unaffected tissue. Clotting occurs on top of the platelet plug when [[Fibrinogen\|Fibrinogen]] (a large soluble [[Protein]]) is converted into [[Fibrin monomers\|Fibrin monomers]] (an insoluble thread-like molecule) by [[Thrombin\|thrombin]]. Fibrin monomers are then crosslinked into Fibrin polymers in the presence of [[Factor XIIIa\|factor XIIIa]] and [[Calcium\|Ca<sup>2+</sup>]].

170044518: Cleaned up some links.

2017-11-24T14:18:27Z

Cleaned up some links.

← Older revision		Revision as of 14:18, 24 November 2017
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	Blood coagulation is the transformation of [[Blood\|blood]] as a liquid into a solid gel like blood "clot". A clot is formed when platelets stick to [[Collagen\|collagen]] exposed by a disrupted blood vessel lining. Other ~~[[Platelets\|~~platelets]] then bind to the initial platelets to form what is called a [[~~Platelets~~\|platelet]] ~~plug~~. The platelet plug is limited to the disrupted area and does not spread to the normal unaffected tissue. Clotting occurs on top of the platelet plug when [[Fibrinogen\|Fibrinogen]] (a large soluble [[Protein]]) is converted into [[Fibrin monomers\|Fibrin monomers]] (an insoluble thread like molecule) by [[Thrombin\|thrombin]]. Fibrin monomers are then crosslinked into Fibrin polymers in the presence of [[Factor XIIIa\|factor XIIIa]] and [[Calcium\|Ca<sup>2+</sup>]].		Blood coagulation is the transformation of [[Blood\|blood]] as a liquid into a solid gel like blood "clot". A clot is formed when [[platelets\|platelets]] stick to [[Collagen\|collagen]] exposed by a disrupted blood vessel lining. Other platelets then bind to the initial platelets to form what is called a [[platelet plug\|platelet plug]]. The platelet plug is limited to the disrupted area and does not spread to the normal unaffected tissue. Clotting occurs on top of the platelet plug when [[Fibrinogen\|Fibrinogen]] (a large soluble [[Protein]]) is converted into [[Fibrin monomers\|Fibrin monomers]] (an insoluble thread like molecule) by [[Thrombin\|thrombin]]. Fibrin monomers are then crosslinked into Fibrin polymers in the presence of [[Factor XIIIa\|factor XIIIa]] and [[Calcium\|Ca<sup>2+</sup>]].

130326405 at 11:45, 24 October 2014

2014-10-24T11:45:00Z

← Older revision		Revision as of 11:45, 24 October 2014
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	Blood coagulation is the transformation of [[Blood\|blood]] as a liquid into a solid gel like blood "clot". A clot is formed when platelets stick to [[Collagen\|collagen]] exposed by a disrupted blood vessel lining. Other platelets then bind to the initial platelets to form what is called a [[Platelets\|platelet]] plug. The platelet plug is limited to the disrupted area and does not spread to the normal unaffected tissue. Clotting occurs on top of the platelet plug when [[Fibrinogen\|Fibrinogen]] (a large soluble pr[[Protein]]~~otein~~) is converted into [[Fibrin monomers\|Fibrin monomers]] (an insoluble thread like molecule) by [[~~thrombin~~\|thrombin]]. Fibrin monomers are then crosslinked into Fibrin polymers in the presence of [[~~factor~~ XIIIa\|factor XIIIa]] and [[Calcium\|Ca<sup>2+</sup>]].		Blood coagulation is the transformation of [[Blood\|blood]] as a liquid into a solid gel like blood "clot". A clot is formed when platelets stick to [[Collagen\|collagen]] exposed by a disrupted blood vessel lining. Other [[Platelets\|platelets]] then bind to the initial platelets to form what is called a [[Platelets\|platelet]] plug. The platelet plug is limited to the disrupted area and does not spread to the normal unaffected tissue. Clotting occurs on top of the platelet plug when [[Fibrinogen\|Fibrinogen]] (a large soluble [[Protein]]) is converted into [[Fibrin monomers\|Fibrin monomers]] (an insoluble thread like molecule) by [[Thrombin\|thrombin]]. Fibrin monomers are then crosslinked into Fibrin polymers in the presence of [[Factor XIIIa\|factor XIIIa]] and [[Calcium\|Ca<sup>2+</sup>]].

Nnjm2 at 01:22, 18 October 2013

2013-10-18T01:22:56Z

← Older revision		Revision as of 01:22, 18 October 2013
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	Blood coagulation is the transformation of blood as a liquid into a solid gel like blood "clot". A clot is formed when platelets stick to collagen exposed by a disrupted blood vessel lining. Other platelets then bind to the initial platelets to form what is called a platelet plug. The platelet plug is limited to the disrupted area and does not spread to the normal unaffected tissue. Clotting occurs on top of the platelet plug when Fibrinogen (a large soluble ~~protein~~) is converted into Fibrin monomers (an insoluble thread like molecule) by thrombin. Fibrin monomers are then crosslinked into Fibrin polymers in the presence of factor XIIIa and ~~Ca2~~+.		Blood coagulation is the transformation of [[Blood\|blood]] as a liquid into a solid gel like blood "clot". A clot is formed when platelets stick to [[Collagen\|collagen]] exposed by a disrupted blood vessel lining. Other platelets then bind to the initial platelets to form what is called a [[Platelets\|platelet]] plug. The platelet plug is limited to the disrupted area and does not spread to the normal unaffected tissue. Clotting occurs on top of the platelet plug when [[Fibrinogen\|Fibrinogen]] (a large soluble pr[[Protein]]otein) is converted into [[Fibrin monomers\|Fibrin monomers]] (an insoluble thread like molecule) by [[thrombin\|thrombin]]. Fibrin monomers are then crosslinked into Fibrin polymers in the presence of [[factor XIIIa\|factor XIIIa]] and [[Calcium\|Ca<sup>2+</sup>]].

120119084: Created page with "Blood coagulation is the transformation of blood as a liquid into a solid gel like blood "clot". A clot is formed when platelets stick to collagen exposed by a disrupted blo..."

2013-10-17T21:21:13Z

Created page with "Blood coagulation is the transformation of blood as a liquid into a solid gel like blood "clot". A clot is formed when platelets stick to collagen exposed by a disrupted blo..."

New page

Blood coagulation is the transformation of blood as a liquid into a solid gel like blood "clot". A clot is formed when platelets stick to collagen exposed by a disrupted blood vessel lining. Other platelets then bind to the initial platelets to form what is called a platelet plug. The platelet plug is limited to the disrupted area and does not spread to the normal unaffected tissue. Clotting occurs on top of the platelet plug when Fibrinogen (a large soluble protein) is converted into Fibrin monomers (an insoluble thread like molecule) by thrombin. Fibrin monomers are then crosslinked into Fibrin polymers in the presence of factor XIIIa and Ca2+.