Nnjm2: Added the references correctly, that is, I added them as explained in the lecture. Cleaned up the text. Added some links (there were none).

2017-12-05T08:13:58Z

Added the references correctly, that is, I added them as explained in the lecture. Cleaned up the text. Added some links (there were none).

← Older revision		Revision as of 08:13, 5 December 2017
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	An E.coli ribosome is a ~~<u>~~ribonucleoprotein~~</u>~~ assembly with a mass of about ~~2500kDa~~. Ribosomes are abundant (10% of total protein and 80% RNA). A ribosome (70S) can be dissociated into large subunit (50S) and a small subunit (30S). The formation of 70S initiation complex is the rate-limiting step in protein synthesis. These subunits can be further split into their consituent proteins and RNAs.		An ''[[E. coli\|E. coli]]'' ribosome is a ribonucleoprotein assembly with a mass of about 2500 kDa. Ribosomes are abundant (10% of total [[protein\|protein]] and 80% [[RNA\|RNA]]). A ribosome (70S) can be dissociated into large subunit (50S) and a small subunit (30S). The formation of 70S initiation complex is the rate-limiting step in [[protein synthesis\|protein synthesis]]. These subunits can be further split into their consituent proteins and RNAs.

	The '''30S subunit''' contains 21 different proteins and a 16S RNA molecule. 16S subunit pairs with purine-rich region called Shine-Dalgano sequence. The number of base pairs linking mRNA and 16S rRNA ranges from 3 to 9. In addition, AUG codon pairs with initiator tRNA.		The '''30S subunit''' contains 21 different proteins and a 16S RNA molecule. 16S subunit pairs with purine-rich region called [[Shine_dalgarno\|Shine-Dalgano sequence]]. The number of base pairs linking [[MRNA\|mRNA]] and 16S [[RRNA\|rRNA]] ranges from 3 to 9. In addition, AUG [[codon\|codon]] pairs with initiator [[tRNA\|tRNA]].

	The '''50S subunit''' conains 34 different proteins and two RNA molecules, a 23S and a 5S species. 23S subunit is important in the formation of peptide bond.		The '''50S subunit''' conains 34 different proteins and two RNA [[molecules\|molecules]], a 23S and a 5S species. 23S subunit is important in the formation of [[peptide bond\|peptide bond]].

	S= Svedberg unit (measure sedimentation rate in centrifuge and thus size)		S = [[Svedberg unit\|Svedberg unit]] (measure sedimentation rate in [[centrifuge\|centrifuge]] and thus size)<ref>Rhodes, Carl Douglas, et al. Student companion to accompany Biochemistry, eighth edition. W.H. Freeman and Company, a Macmillan Education Company, 2015. (pg 902)</ref>.<br>

			=== References ===

			<references /><br>


	~~References:~~

	~~Rhodes, Carl Douglas, et al. Student companion to accompany Biochemistry, eighth edition. W.H. Freeman and Company, a Macmillan Education Company, 2015. (pg 902)~~

170757582: Created page with "An E.coli ribosome is a ribonucleoprotein assembly with a mass of about 2500kDa. Ribosomes are abundant (10% of total protein and 80% RNA). A ribosome (70S) can be dissoci..."

2017-12-04T11:27:10Z

Created page with "An E.coli ribosome is a <u>ribonucleoprotein</u> assembly with a mass of about 2500kDa. Ribosomes are abundant (10% of total protein and 80% RNA). A ribosome (70S) can be dissoci..."

New page

An E.coli ribosome is a <u>ribonucleoprotein</u> assembly with a mass of about 2500kDa. Ribosomes are abundant (10% of total protein and 80% RNA). A ribosome (70S) can be dissociated into large subunit (50S) and a small subunit (30S). The formation of 70S initiation complex is the rate-limiting step in protein synthesis. These subunits can be further split into their consituent proteins and RNAs.

The '''30S subunit''' contains 21 different proteins and a 16S RNA molecule. 16S subunit pairs with purine-rich region called Shine-Dalgano sequence. The number of base pairs linking mRNA and 16S rRNA ranges from 3 to 9. In addition, AUG codon pairs with initiator tRNA.

The '''50S subunit''' conains 34 different proteins and two RNA molecules, a 23S and a 5S species. 23S subunit is important in the formation of peptide bond.

S= Svedberg unit (measure sedimentation rate in centrifuge and thus size)

References:

Rhodes, Carl Douglas, et al. Student companion to accompany Biochemistry, eighth edition. W.H. Freeman and Company, a Macmillan Education Company, 2015. (pg 902)

Composition of prokaryotic ribosome - Revision history

Nnjm2: Added the references correctly, that is, I added them as explained in the lecture. Cleaned up the text. Added some links (there were none).

170757582: Created page with "An E.coli ribosome is a ribonucleoprotein assembly with a mass of about 2500kDa. Ribosomes are abundant (10% of total protein and 80% RNA). A ribosome (70S) can be dissoci..."