Huntington’s disease - Revision history

Nnjm2 at 08:47, 28 October 2015

2015-10-28T08:47:30Z

← Older revision		Revision as of 08:47, 28 October 2015
Line 1:		Line 1:
	Huntington’s disease is a [[~~neurodegenerative~~ genetic disorder\|neurodegenerative genetic disorder]] on the [[~~brain~~\|brain]] and [[~~Nervous_system~~\|nervous system]]. It is a slowly progressive condition with symptoms such as lack of [[Muscle\|muscle]] coordination, cognitive decline and behavioural symptoms, it is a unique disease as symptoms often do not show until 35-40 years of age.		Huntington’s disease is a [[Neurodegenerative genetic disorder\|neurodegenerative genetic disorder]] on the [[Brain\|brain]] and [[Nervous system\|nervous system]]. It is a slowly progressive condition with symptoms such as lack of [[Muscle\|muscle]] coordination, cognitive decline and behavioural symptoms, it is a unique disease as symptoms often do not show until 35-40 years of age.

	It is caused due to a defected [[~~gene~~\|gene]] inherited from the parents, with the gene fault being carried on [[~~chromosome~~ 4\|chromosome 4]]. Huntington’s is a [[~~Autosomal_dominant~~\|autosomal dominant disease]], meaning it can be inherited if just one parent carries the gene defect, so every child they have will have a 50:50 chance of inheriting the gene.		It is caused due to a defected [[Gene\|gene]] inherited from the parents, with the gene fault being carried on [[Chromosome 4\|chromosome 4]]. Huntington’s is a [[Autosomal dominant\|autosomal dominant disease]], meaning it can be inherited if just one parent carries the gene defect, so every child they have will have a 50:50 chance of inheriting the gene.

	The gene is non functional due to a set of repeats of the protein HTT <ref>http://ghr.nlm.nih.gov/condition/huntington-disease</ref>.The gene defect leads to specific brain chemical proteins, not being made in the brain as normal. This is thought to lead to damage and death of some neurons in particular regions of the brain (the basal ganglia and cortex).		The gene is non functional due to a set of repeats of the protein HTT <ref>http://ghr.nlm.nih.gov/condition/huntington-disease</ref>.The gene defect leads to specific brain chemical proteins, not being made in the brain as normal. This is thought to lead to damage and death of some neurons in particular regions of the brain (the basal ganglia and cortex).

	The fact Huntington’s is a slowly progressive condition means symptoms will gradually develop and worsen as time goes on. People usually live with Huntington’s disease for 10 to 25 years after symptoms first appear, with death usually from an infection such as pneumonia <ref>http://www.patient.co.uk/health/huntingtons-disease-leaflet</ref>.		The fact Huntington’s is a slowly progressive condition means symptoms will gradually develop and worsen as time goes on. People usually live with Huntington’s disease for 10 to 25 years after symptoms first appear, with death usually from an infection such as pneumonia <ref>http://www.patient.co.uk/health/huntingtons-disease-leaflet</ref>.<br>

			=== References ===

	=== References ===

	<references />		<references />

140094660 at 13:40, 22 October 2015

2015-10-22T13:40:50Z

← Older revision		Revision as of 13:40, 22 October 2015
Line 3:		Line 3:
	It is caused due to a defected [[gene\|gene]] inherited from the parents, with the gene fault being carried on [[chromosome 4\|chromosome 4]]. Huntington’s is a [[Autosomal_dominant\|autosomal dominant disease]], meaning it can be inherited if just one parent carries the gene defect, so every child they have will have a 50:50 chance of inheriting the gene.		It is caused due to a defected [[gene\|gene]] inherited from the parents, with the gene fault being carried on [[chromosome 4\|chromosome 4]]. Huntington’s is a [[Autosomal_dominant\|autosomal dominant disease]], meaning it can be inherited if just one parent carries the gene defect, so every child they have will have a 50:50 chance of inheriting the gene.

	The gene is non functional due to a set of repeats of the protein HTT.The gene defect leads to specific brain chemical proteins, not being made in the brain as normal. This is thought to lead to damage and death of some neurons in particular regions of the brain (the basal ganglia and cortex).		The gene is non functional due to a set of repeats of the protein HTT <ref>http://ghr.nlm.nih.gov/condition/huntington-disease</ref>.The gene defect leads to specific brain chemical proteins, not being made in the brain as normal. This is thought to lead to damage and death of some neurons in particular regions of the brain (the basal ganglia and cortex).

	The fact Huntington’s is a slowly progressive condition means symptoms will gradually develop and worsen as time goes on. People usually live with Huntington’s disease for 10 to 25 years after symptoms first appear, with death usually from an infection such as pneumonia <ref>http://www.patient.co.uk/health/huntingtons-disease-leaflet</ref>.		The fact Huntington’s is a slowly progressive condition means symptoms will gradually develop and worsen as time goes on. People usually live with Huntington’s disease for 10 to 25 years after symptoms first appear, with death usually from an infection such as pneumonia <ref>http://www.patient.co.uk/health/huntingtons-disease-leaflet</ref>.
Line 10:		Line 10:

	=== References ===		=== References ===
	~~http://ghr.nlm.nih.gov/condition/huntington-disease~~

	<references />		<references />

140094660 at 13:39, 22 October 2015

2015-10-22T13:39:57Z

← Older revision		Revision as of 13:39, 22 October 2015
Line 3:		Line 3:
	It is caused due to a defected [[gene\|gene]] inherited from the parents, with the gene fault being carried on [[chromosome 4\|chromosome 4]]. Huntington’s is a [[Autosomal_dominant\|autosomal dominant disease]], meaning it can be inherited if just one parent carries the gene defect, so every child they have will have a 50:50 chance of inheriting the gene.		It is caused due to a defected [[gene\|gene]] inherited from the parents, with the gene fault being carried on [[chromosome 4\|chromosome 4]]. Huntington’s is a [[Autosomal_dominant\|autosomal dominant disease]], meaning it can be inherited if just one parent carries the gene defect, so every child they have will have a 50:50 chance of inheriting the gene.

	The gene defect leads to specific brain chemical proteins, not being made in the brain as normal. This is thought to lead to damage and death of some neurons in particular regions of the brain (the basal ganglia and cortex).		The gene is non functional due to a set of repeats of the protein HTT.The gene defect leads to specific brain chemical proteins, not being made in the brain as normal. This is thought to lead to damage and death of some neurons in particular regions of the brain (the basal ganglia and cortex).

	The fact Huntington’s is a slowly progressive condition means symptoms will gradually develop and worsen as time goes on. People usually live with Huntington’s disease for 10 to 25 years after symptoms first appear, with death usually from an infection such as pneumonia <ref>http://www.patient.co.uk/health/huntingtons-disease-leaflet</ref>.		The fact Huntington’s is a slowly progressive condition means symptoms will gradually develop and worsen as time goes on. People usually live with Huntington’s disease for 10 to 25 years after symptoms first appear, with death usually from an infection such as pneumonia <ref>http://www.patient.co.uk/health/huntingtons-disease-leaflet</ref>.



	=== References ===		=== References ===
			http://ghr.nlm.nih.gov/condition/huntington-disease

	<references />		<references />

Nnjm2: Cleaned up the entry. Added in some links. Sorted out the references. Poorly formated. Didn't follow publication guidelines.

2014-10-22T07:04:33Z

Cleaned up the entry. Added in some links. Sorted out the references. Poorly formated. Didn't follow publication guidelines.

← Older revision		Revision as of 07:04, 22 October 2014
Line 1:		Line 1:
	Huntington’s disease is a neurodegenerative genetic disorder on the brain and nervous system. It is a slowly progressive condition with symptoms such as lack of muscle coordination, cognitive decline and behavioural symptoms, it is a unique disease as symptoms often do not show until 35-40 years of age.~~<br>~~It is caused due to a defected gene inherited from the parents, with the gene fault being carried on chromosome 4. Huntington’s is a autosomal dominant disease, meaning it can be inherited if just one parent carries the gene defect, so every child they have will have a 50:50 chance of inheriting the gene.~~<br>~~The gene defect leads to specific brain chemical proteins, not being made in the brain as normal. This is thought to lead to damage and death of some neurons in particular regions of the brain (the basal ganglia and cortex). ~~<br>~~The fact Huntington’s is a slowly progressive condition means symptoms will gradually develop and worsen as time goes on. People usually live with Huntington’s disease for 10 to 25 years after symptoms first appear, with death usually from an infection such as pneumonia~~.<br>~~<ref>http://www.patient.co.uk/health/huntingtons-disease-leaflet</ref><references />		Huntington’s disease is a [[neurodegenerative genetic disorder\|neurodegenerative genetic disorder]] on the [[brain\|brain]] and [[Nervous_system\|nervous system]]. It is a slowly progressive condition with symptoms such as lack of [[Muscle\|muscle]] coordination, cognitive decline and behavioural symptoms, it is a unique disease as symptoms often do not show until 35-40 years of age.

			It is caused due to a defected [[gene\|gene]] inherited from the parents, with the gene fault being carried on [[chromosome 4\|chromosome 4]]. Huntington’s is a [[Autosomal_dominant\|autosomal dominant disease]], meaning it can be inherited if just one parent carries the gene defect, so every child they have will have a 50:50 chance of inheriting the gene.

			The gene defect leads to specific brain chemical proteins, not being made in the brain as normal. This is thought to lead to damage and death of some neurons in particular regions of the brain (the basal ganglia and cortex).

			The fact Huntington’s is a slowly progressive condition means symptoms will gradually develop and worsen as time goes on. People usually live with Huntington’s disease for 10 to 25 years after symptoms first appear, with death usually from an infection such as pneumonia <ref>http://www.patient.co.uk/health/huntingtons-disease-leaflet</ref>.

			=== References ===

			<references />

130156846: Created page with "Huntington’s disease is a neurodegenerative genetic disorder on the brain and nervous system. It is a slowly progressive condition with symptoms such as lack of muscle coordina..."

2014-10-17T14:16:02Z

Created page with "Huntington’s disease is a neurodegenerative genetic disorder on the brain and nervous system. It is a slowly progressive condition with symptoms such as lack of muscle coordina..."

New page

Huntington’s disease is a neurodegenerative genetic disorder on the brain and nervous system. It is a slowly progressive condition with symptoms such as lack of muscle coordination, cognitive decline and behavioural symptoms, it is a unique disease as symptoms often do not show until 35-40 years of age.<br>It is caused due to a defected gene inherited from the parents, with the gene fault being carried on chromosome 4. Huntington’s is a autosomal dominant disease, meaning it can be inherited if just one parent carries the gene defect, so every child they have will have a 50:50 chance of inheriting the gene.<br>The gene defect leads to specific brain chemical proteins, not being made in the brain as normal. This is thought to lead to damage and death of some neurons in particular regions of the brain (the basal ganglia and cortex). <br>The fact Huntington’s is a slowly progressive condition means symptoms will gradually develop and worsen as time goes on. People usually live with Huntington’s disease for 10 to 25 years after symptoms first appear, with death usually from an infection such as pneumonia.<br><ref>http://www.patient.co.uk/health/huntingtons-disease-leaflet</ref><references />