Ligand-gated sodium channels - Revision history

Nnjm2 at 09:17, 6 December 2017

2017-12-06T09:17:10Z

← Older revision		Revision as of 09:17, 6 December 2017
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	Ligand-gated Na+ channels are found in the postsynaptic membrane of the neuromuscular junction<ref name="al">Alberts, et al. Essential Cell Biology. 4th edition. Abingdon. Garland Science. Page 410-412</ref>. After a neurotransmitter (acetylcholine) binds to its receptor the channel opens (undergoes a conformational change) allowing Na<sup>+</sup> to enter the motor endplate and K<sup>+</sup> to flow out<ref name="al">Alberts, et al. Essential Cell Biology. 4th edition. Abingdon. Garland Science. Page 410-412</ref><ref>Mheducationcom. Animation: Receptors Linked to a Channel Protein. [Accessed 5 December 2017]. Available from: http://highered.mheducation.com/sites/0072495855/student_view0/chapter2/animation__receptors_linked_to_a_channel_protein.html</ref>. This causes the motor endplate to depolarise. If the end plate potential reaches a high enough potential it will go on to trigger an action potential in the cell<ref name="al">Alberts, et al. Essential Cell Biology. 4th edition. Abingdon. Garland Science. Page 410-412</ref>.		Ligand-gated Na+ channels are found in the postsynaptic membrane of the neuromuscular junction<ref name="al">Alberts, et al. Essential Cell Biology. 4th edition. Abingdon. Garland Science. Page 410-412</ref>. After a neurotransmitter (acetylcholine) binds to its receptor the channel opens (undergoes a conformational change) allowing Na<sup>+</sup> to enter the motor endplate and K<sup>+</sup> to flow out<ref name="al">Alberts, et al. Essential Cell Biology. 4th edition. Abingdon. Garland Science. Page 410-412</ref><ref>Mheducationcom. Animation: Receptors Linked to a Channel Protein. [Accessed 5 December 2017]. Available from: http://highered.mheducation.com/sites/0072495855/student_view0/chapter2/animation__receptors_linked_to_a_channel_protein.html</ref>. This causes the motor endplate to depolarise. If the end plate potential reaches a high enough potential it will go on to trigger an action potential in the cell<ref name="al">Alberts, et al. Essential Cell Biology. 4th edition. Abingdon. Garland Science. Page 410-412</ref>.

	=== References ===		=== References ===

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Nnjm2: Added the references correctly, that is, I added them as explained in the lecture. Cleaned up the text.

2017-12-06T09:17:00Z

Added the references correctly, that is, I added them as explained in the lecture. Cleaned up the text.

← Older revision		Revision as of 09:17, 6 December 2017
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	~~ ~~Ligand gated Na+ channels are found in the ~~post synaptic~~ membrane of the neuromuscular junction ~~(1)~~. After a neurotransmitter (acetylcholine) binds to its receptor the channel opens (undergoes a conformational change) allowing Na+ to enter the motor endplate and K+ to flow out ~~(1) (2). This causes the motor endplate to depolarise. If the end plate potential reaches a high enough potential it will go on to trigger an action potential in the cell (1).~~<~~br> <br~~>~~References<br>1.~~ Alberts, et al. Essential Cell Biology. 4th edition. Abingdon. Garland ~~science~~. Page 410-412<br>2. Mheducationcom. Animation: Receptors Linked to a Channel Protein. [Accessed 5 December 2017]. Available from: http://highered.mheducation.com/sites/0072495855/student_view0/chapter2/animation__receptors_linked_to_a_channel_protein.html		Ligand-gated Na+ channels are found in the postsynaptic membrane of the neuromuscular junction<ref name="al">Alberts, et al. Essential Cell Biology. 4th edition. Abingdon. Garland Science. Page 410-412</ref>. After a neurotransmitter (acetylcholine) binds to its receptor the channel opens (undergoes a conformational change) allowing Na<sup>+</sup> to enter the motor endplate and K<sup>+</sup> to flow out<ref name="al">Alberts, et al. Essential Cell Biology. 4th edition. Abingdon. Garland Science. Page 410-412</ref><ref>Mheducationcom. Animation: Receptors Linked to a Channel Protein. [Accessed 5 December 2017]. Available from: http://highered.mheducation.com/sites/0072495855/student_view0/chapter2/animation__receptors_linked_to_a_channel_protein.html</ref>. This causes the motor endplate to depolarise. If the end plate potential reaches a high enough potential it will go on to trigger an action potential in the cell<ref name="al">Alberts, et al. Essential Cell Biology. 4th edition. Abingdon. Garland Science. Page 410-412</ref>.

			=== References ===

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2017-12-05T23:53:15Z

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 Ligand gated Na+ channels are found in the post synaptic membrane of the neuromuscular junction (1). After a neurotransmitter (acetylcholine) binds to its receptor the channel opens (undergoes a conformational change) allowing Na+ to enter the motor endplate and K+ to flow out (1) (2). This causes the motor endplate to depolarise. If the end plate potential reaches a high enough potential it will go on to trigger an action potential in the cell (1).<br> <br>References<br>1. Alberts, et al. Essential Cell Biology. 4th edition. Abingdon. Garland science. Page 410-412<br>2. Mheducationcom. Animation: Receptors Linked to a Channel Protein. [Accessed 5 December 2017]. Available from: http://highered.mheducation.com/sites/0072495855/student_view0/chapter2/animation__receptors_linked_to_a_channel_protein.html