Multi-drug resistance (MDR) - Revision history

160248773 at 13:10, 23 October 2017

2017-10-23T13:10:17Z

← Older revision		Revision as of 13:10, 23 October 2017
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	Multi-drug resistance is a condition where [[Cancer\|cancer]] cells are resistant to [[Chemotherapy\|chemotherapy]] drugs due to the presence on a drug eflux pump called the [[P-glycoprotein\|p-glycoprotein]] that actively pumps out drugs from the cell. [[P-glycoprotein\|P-glycoprotein]] in normal gut [[Epithelial cells\|epithelial cells]] help to expell toxic substances in the food we eat, but this is up-regulated in [[Cancer\|cancer]] cells. The p-[[Glycoprotein\|glycoprotein]] is part of the [[ABC transporter superfamily\|ABC transporter superfamily]].		Multi-drug resistance is a condition where [[Cancer\|cancer]] cells are resistant to [[Chemotherapy\|chemotherapy]] drugs due to the presence on a drug eflux pump called the [[P-glycoprotein\|p-glycoprotein]] that actively pumps out drugs from the cell. [[P-glycoprotein\|P-glycoprotein]] in normal gut [[Epithelial cells\|epithelial cells]] help to expell toxic substances in the food we eat, but this is up-regulated in [[Cancer\|cancer]] cells. The p-[[Glycoprotein\|glycoprotein]] is part of the [[ABC transporter superfamily\|ABC transporter superfamily]]. Also see [[Antibiotic_resistance\|Antibiotic Resistance]].

Nnjm2 at 14:31, 14 October 2013

2013-10-14T14:31:25Z

← Older revision		Revision as of 14:31, 14 October 2013
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	Multi-drug resistance is a condition where [[Cancer\|cancer]] cells are resistant to chemotherapy drugs due to the presence on a drug eflux pump called the [[P-glycoprotein\|p-glycoprotein]] that actively pumps out drugs from the cell. P-glycoprotein in normal gut [[Epithelial cells\|epithelial cells]] help to expell toxic substances in the food we eat, but this is up-regulated in [[Cancer\|cancer]] cells. The p-[[Glycoprotein\|glycoprotein]] is part of the [[ABC transporter superfamily\|ABC transporter superfamily]].		Multi-drug resistance is a condition where [[Cancer\|cancer]] cells are resistant to [[Chemotherapy\|chemotherapy]] drugs due to the presence on a drug eflux pump called the [[P-glycoprotein\|p-glycoprotein]] that actively pumps out drugs from the cell. [[P-glycoprotein\|P-glycoprotein]] in normal gut [[Epithelial cells\|epithelial cells]] help to expell toxic substances in the food we eat, but this is up-regulated in [[Cancer\|cancer]] cells. The p-[[Glycoprotein\|glycoprotein]] is part of the [[ABC transporter superfamily\|ABC transporter superfamily]].

120038305 at 14:20, 14 October 2013

2013-10-14T14:20:10Z

← Older revision		Revision as of 14:20, 14 October 2013
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	Multi-drug resistance is a condition where cancer cells are resistant to chemotherapy drugs due to the presence on a drug eflux pump called the [[P-glycoprotein\|p-glycoprotein]] that actively pumps out drugs from the cell. P-glycoprotein in normal [[~~Epithelial_cells~~\|epithelial cells]] help to expell toxic substances in the food we eat, but this is up-regulated in cancer cells. The p-[[~~glycoprotein~~\|glycoprotein]] is part of the [[ABC transporter superfamily\|ABC transporter superfamily]].		Multi-drug resistance is a condition where [[Cancer\|cancer]] cells are resistant to chemotherapy drugs due to the presence on a drug eflux pump called the [[P-glycoprotein\|p-glycoprotein]] that actively pumps out drugs from the cell. P-glycoprotein in normal gut [[Epithelial cells\|epithelial cells]] help to expell toxic substances in the food we eat, but this is up-regulated in [[Cancer\|cancer]] cells. The p-[[Glycoprotein\|glycoprotein]] is part of the [[ABC transporter superfamily\|ABC transporter superfamily]].

Nnjm2 at 18:35, 29 November 2011

2011-11-29T18:35:12Z

← Older revision		Revision as of 18:35, 29 November 2011
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	Multi-drug resistance is a condition where cancer cells are resistant to chemotherapy drugs due to the presence on a drug eflux pump called the p-glycoprotein that actively pumps out drugs from the cell. P-glycoprotein in normal epithelial cells help to expell toxic substances in the food we eat, but this is up-regulated in cancer cells. The p-glycoprotein is part of the ABC transporter superfamily.		Multi-drug resistance is a condition where cancer cells are resistant to chemotherapy drugs due to the presence on a drug eflux pump called the [[P-glycoprotein\|p-glycoprotein]] that actively pumps out drugs from the cell. P-glycoprotein in normal [[Epithelial_cells\|epithelial cells]] help to expell toxic substances in the food we eat, but this is up-regulated in cancer cells. The p-[[glycoprotein\|glycoprotein]] is part of the [[ABC transporter superfamily\|ABC transporter superfamily]].

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2011-11-29T15:26:28Z

Created page with "Multi-drug resistance is a condition where cancer cells are resistant to chemotherapy drugs due to the presence on a drug eflux pump called the p-glycoprotein that actively pumps..."

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Multi-drug resistance is a condition where cancer cells are resistant to chemotherapy drugs due to the presence on a drug eflux pump called the p-glycoprotein that actively pumps out drugs from the cell. P-glycoprotein in normal epithelial cells help to expell toxic substances in the food we eat, but this is up-regulated in cancer cells. The p-glycoprotein is part of the ABC transporter superfamily.