https://teaching.ncl.ac.uk/bms/wiki//index.php?action=history&feed=atom&title=Promoters Promoters - Revision history 2026-04-10T17:53:15Z Revision history for this page on the wiki MediaWiki 1.44.0 https://teaching.ncl.ac.uk/bms/wiki//index.php?title=Promoters&diff=21863&oldid=prev Nnjm2: Cleaned up the text. Added some links. Page needs some references. 2018-11-03T16:49:13Z <p>Cleaned up the text. Added some links. Page needs some references.</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 16:49, 3 November 2018</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>The DNA region or sequence that helps in initiating <del style="font-weight: bold; text-decoration: none;">transciption </del>is known as the promoter. <del style="font-weight: bold; text-decoration: none;">Rna </del>polymerase binds to the promoter and further initiates transcription of a gene.<del style="font-weight: bold; text-decoration: none;">&lt;br&gt;They can be present close to the transcription start site or many kilobases away.&amp;nbsp;&lt;br&gt;Based on their location they can be characterised as Core/Basal promoter elements or the Regulatory region elements.&lt;br&gt;</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>The <ins style="font-weight: bold; text-decoration: none;">[[</ins>DNA<ins style="font-weight: bold; text-decoration: none;">|DNA]] </ins>region or sequence that helps in initiating <ins style="font-weight: bold; text-decoration: none;">[[transcription|transcription]] </ins>is known as the promoter. <ins style="font-weight: bold; text-decoration: none;">[[RNA polymerase|RNA </ins>polymerase<ins style="font-weight: bold; text-decoration: none;">]] </ins>binds to the promoter and further initiates transcription of a <ins style="font-weight: bold; text-decoration: none;">[[gene|</ins>gene<ins style="font-weight: bold; text-decoration: none;">]]</ins>.  </div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Core/Basal elements include TATA boxes and Initiator Sequences (Inr). CpG islands are also present in mammals.<del style="font-weight: bold; text-decoration: none;">&lt;br&gt;</del>Regulatory region elements include UAS/enhancer elements and URS/silencer elements.<del style="font-weight: bold; text-decoration: none;">&lt;br&gt;&lt;br&gt;</del>Other promoters are Downstream Promoter elements (DPE) and BRE (TFIIB recognition element).<del style="font-weight: bold; text-decoration: none;">&lt;br&gt;</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">They can be present close to the [[transcription start site|transcription start site]] or many kilobases away. </ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Based on their location they can be characterised as Core/[[Basal Promoter Element|Basal Promoter Elements]] or the [[Regulatory Region Element|Regulatory Region Elements]]. </ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Core/Basal elements include <ins style="font-weight: bold; text-decoration: none;">[[TATA_box|</ins>TATA boxes<ins style="font-weight: bold; text-decoration: none;">]] </ins>and <ins style="font-weight: bold; text-decoration: none;">[[Initiator Sequence|</ins>Initiator Sequences<ins style="font-weight: bold; text-decoration: none;">]] </ins>(Inr). <ins style="font-weight: bold; text-decoration: none;">[[CpG_island|</ins>CpG islands<ins style="font-weight: bold; text-decoration: none;">]] </ins>are also present in <ins style="font-weight: bold; text-decoration: none;">[[mammals|</ins>mammals<ins style="font-weight: bold; text-decoration: none;">]]</ins>.  </div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Regulatory region elements include UAS/enhancer elements and URS/silencer elements.  </div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Other promoters are Downstream Promoter elements (DPE) and BRE (TFIIB recognition element).</div></td></tr> </table> Nnjm2 https://teaching.ncl.ac.uk/bms/wiki//index.php?title=Promoters&diff=21861&oldid=prev 170649128: New page 2018-11-03T16:11:59Z <p>New page</p> <p><b>New page</b></p><div>The DNA region or sequence that helps in initiating transciption is known as the promoter. Rna polymerase binds to the promoter and further initiates transcription of a gene.&lt;br&gt;They can be present close to the transcription start site or many kilobases away.&amp;nbsp;&lt;br&gt;Based on their location they can be characterised as Core/Basal promoter elements or the Regulatory region elements.&lt;br&gt;<br /> <br /> Core/Basal elements include TATA boxes and Initiator Sequences (Inr). CpG islands are also present in mammals.&lt;br&gt;Regulatory region elements include UAS/enhancer elements and URS/silencer elements.&lt;br&gt;&lt;br&gt;Other promoters are Downstream Promoter elements (DPE) and BRE (TFIIB recognition element).&lt;br&gt;</div> 170649128