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	<id>https://teaching.ncl.ac.uk/bms/wiki//index.php?action=history&amp;feed=atom&amp;title=Rough_endoplasmic_reticulum</id>
	<title>Rough endoplasmic reticulum - Revision history</title>
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	<link rel="alternate" type="text/html" href="https://teaching.ncl.ac.uk/bms/wiki//index.php?title=Rough_endoplasmic_reticulum&amp;action=history"/>
	<updated>2026-04-10T12:57:07Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://teaching.ncl.ac.uk/bms/wiki//index.php?title=Rough_endoplasmic_reticulum&amp;diff=5217&amp;oldid=prev</id>
		<title>Nnjm2: Replaced content with &quot;See Rough Endoplasmic Reticulum&quot;</title>
		<link rel="alternate" type="text/html" href="https://teaching.ncl.ac.uk/bms/wiki//index.php?title=Rough_endoplasmic_reticulum&amp;diff=5217&amp;oldid=prev"/>
		<updated>2011-12-01T22:20:26Z</updated>

		<summary type="html">&lt;p&gt;Replaced content with &amp;quot;See &lt;a href=&quot;/bms/wiki/index.php/Rough_Endoplasmic_Reticulum&quot; title=&quot;Rough Endoplasmic Reticulum&quot;&gt;Rough Endoplasmic Reticulum&lt;/a&gt;&amp;quot;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 22:20, 1 December 2011&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l1&quot;&gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Rough [[Endoplasmic reticulum|endoplasmic reticulum]] is an organelle found in [[Eukaryotic cells|eukaryotic cells]]. Its main function is to produce [[Proteins|proteins]]. &amp;lt;br&amp;gt;It is made up of cisternae, tubules and [[Vesicles|vesicles]]. The cisternae are made up of flattened membrane disks, which are involved in the modification of [[Proteins|proteins]]. They are held together by the &lt;/del&gt;[[&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Cytoskeleton&lt;/del&gt;|&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;cytoskeleton]]. The rough [[Endoplasmic reticulum|endoplasmic reticulum]] also contains a [[Perinuclear space|perinuclear space]], which is the space between the inner and outer [[Phospholipid|phospholipid]] membrane. The membrane is continuous to the [[Nuclear membrane|nuclear membrane]]. However, it isn’t continuous to the [[Golgi apparatus|Golgi apparatus]]. [[Proteins|Proteins]] are transferred from the &lt;/del&gt;Rough &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;endoplasmic reticulum to the [[Golgi apparatus|Golgi apparatus]] via membrane-bound vesicles. &amp;lt;br&amp;gt;The reason why it is rough endoplasmic reticulum is because of the [[Ribosomes|ribosomes]] attached to the [[Endoplasmic reticulum|endoplasmic reticulum]]. These [[Ribosomes|ribosomes]] are constantly being attached and detached from the ER because they are not part of the stable [[Organelles|organelle]]. They attach when the [[Ribosomes|ribosome]] begins to synthesis a [[Proteins|protein]] which is going to be secreted ([[Secretory pathway|secretory pathway]]).&amp;lt;br&amp;gt;Rough [[Endoplasmic reticulum|endoplasmic reticulum]] has a number of functions. One of the main functions of the rough [[&lt;/del&gt;Endoplasmic &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;reticulum|endoplasmic reticulum]] is to produce and process specific proteins. These are the exported through the [[Secretory pathway|secretory pathway]]. After they are exported via membrane [[Vesicles|vesicles]], they can be sent to the [[Golgi apparatus|Golgi Apparatus]] to be further processed or to [[Organelles|organelles]]. They can even be exported to outside the cell and into another part of the body. [[Ribosomes|Ribosomes]] also create [[proteins|proteins&lt;/del&gt;]] &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;which are embedded into the rough endoplasmic reticulum for further processing (integral membrane proteins). Water soluble proteins are created too, which are exported through the membrane into the lumen &amp;lt;ref&amp;gt;http://www.buzzle.com/articles/rough-endoplasmic-reticulum-function.html&amp;lt;/ref&amp;gt;. &amp;lt;br&amp;gt; &lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;See &lt;/ins&gt;[[&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Rough_Endoplasmic_Reticulum&lt;/ins&gt;|Rough Endoplasmic &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Reticulum&lt;/ins&gt;]]&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt; &lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-added&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;=== References ===&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-added&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt; &lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-added&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;references /&amp;gt;&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-added&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Nnjm2</name></author>
	</entry>
	<entry>
		<id>https://teaching.ncl.ac.uk/bms/wiki//index.php?title=Rough_endoplasmic_reticulum&amp;diff=2803&amp;oldid=prev</id>
		<title>Nnjm2 at 21:13, 10 January 2011</title>
		<link rel="alternate" type="text/html" href="https://teaching.ncl.ac.uk/bms/wiki//index.php?title=Rough_endoplasmic_reticulum&amp;diff=2803&amp;oldid=prev"/>
		<updated>2011-01-10T21:13:30Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 21:13, 10 January 2011&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l1&quot;&gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Rough [[Endoplasmic reticulum|endoplasmic reticulum]] is an organelle found in [[Eukaryotic cells|eukaryotic cells]]. Its main function is to produce [[Proteins|proteins]]. &amp;lt;br&amp;gt;It is made up of cisternae, tubules and [[Vesicles|vesicles]]. The cisternae are made up of flattened membrane disks, which are involved in the modification of [[Proteins|proteins]]. They are held together by the [[Cytoskeleton|cytoskeleton]]. The rough [[Endoplasmic reticulum|endoplasmic reticulum]] also contains a [[Perinuclear space|perinuclear space]], which is the space between the inner and outer [[Phospholipid|phospholipid]] membrane. The membrane is continuous to the [[Nuclear membrane|nuclear membrane]]. However, it isn’t continuous to the [[Golgi apparatus|Golgi apparatus]]. [[Proteins|Proteins]] are transferred from the Rough endoplasmic reticulum to the [[Golgi apparatus|Golgi apparatus]] via membrane-bound vesicles. &amp;lt;br&amp;gt;The reason why it is rough endoplasmic reticulum is because of the [[Ribosomes|ribosomes]] attached to the [[Endoplasmic reticulum|endoplasmic reticulum]]. These [[Ribosomes|ribosomes]] are constantly being attached and detached from the ER because they are not part of the stable [[Organelles|organelle]]. They attach when the [[Ribosomes|ribosome]] begins to synthesis a [[Proteins|protein]] which is going to be secreted ([[Secretory pathway|secretory pathway]]).&amp;lt;br&amp;gt;Rough [[Endoplasmic reticulum|endoplasmic reticulum]] has a number of functions. One of the main functions of the rough [[Endoplasmic reticulum|endoplasmic reticulum]] is to produce and process specific proteins. These are the exported through the [[Secretory pathway|secretory pathway]]. After they are exported via membrane [[Vesicles|vesicles]], they can be sent to the [[Golgi apparatus|Golgi Apparatus]] to be further processed or to organelles. They can even be exported to outside the cell and into another part of the body. [[Ribosomes|Ribosomes]] also create proteins which are embedded into the rough endoplasmic reticulum for further processing (integral membrane proteins). Water soluble proteins are created too, which are exported through the membrane into the lumen. &amp;lt;br&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Rough [[Endoplasmic reticulum|endoplasmic reticulum]] is an organelle found in [[Eukaryotic cells|eukaryotic cells]]. Its main function is to produce [[Proteins|proteins]]. &amp;lt;br&amp;gt;It is made up of cisternae, tubules and [[Vesicles|vesicles]]. The cisternae are made up of flattened membrane disks, which are involved in the modification of [[Proteins|proteins]]. They are held together by the [[Cytoskeleton|cytoskeleton]]. The rough [[Endoplasmic reticulum|endoplasmic reticulum]] also contains a [[Perinuclear space|perinuclear space]], which is the space between the inner and outer [[Phospholipid|phospholipid]] membrane. The membrane is continuous to the [[Nuclear membrane|nuclear membrane]]. However, it isn’t continuous to the [[Golgi apparatus|Golgi apparatus]]. [[Proteins|Proteins]] are transferred from the Rough endoplasmic reticulum to the [[Golgi apparatus|Golgi apparatus]] via membrane-bound vesicles. &amp;lt;br&amp;gt;The reason why it is rough endoplasmic reticulum is because of the [[Ribosomes|ribosomes]] attached to the [[Endoplasmic reticulum|endoplasmic reticulum]]. These [[Ribosomes|ribosomes]] are constantly being attached and detached from the ER because they are not part of the stable [[Organelles|organelle]]. They attach when the [[Ribosomes|ribosome]] begins to synthesis a [[Proteins|protein]] which is going to be secreted ([[Secretory pathway|secretory pathway]]).&amp;lt;br&amp;gt;Rough [[Endoplasmic reticulum|endoplasmic reticulum]] has a number of functions. One of the main functions of the rough [[Endoplasmic reticulum|endoplasmic reticulum]] is to produce and process specific proteins. These are the exported through the [[Secretory pathway|secretory pathway]]. After they are exported via membrane [[Vesicles|vesicles]], they can be sent to the [[Golgi apparatus|Golgi Apparatus]] to be further processed or to &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Organelles|&lt;/ins&gt;organelles&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]]&lt;/ins&gt;. They can even be exported to outside the cell and into another part of the body. [[Ribosomes|Ribosomes]] also create &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[proteins|&lt;/ins&gt;proteins&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]] &lt;/ins&gt;which are embedded into the rough endoplasmic reticulum for further processing (integral membrane proteins). Water soluble proteins are created too, which are exported through the membrane into the lumen &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;ref&amp;gt;http://www.buzzle.com/articles/rough-endoplasmic-reticulum-function.html&amp;lt;/ref&amp;gt;&lt;/ins&gt;. &amp;lt;br&amp;gt;  &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;references /&amp;gt;&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[http://www.buzzle.com/articles/rough-endoplasmic-reticulum-function.html http://www.buzzle.com/articles/rough-endoplasmic-reticulum-function.html]&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;=== References ===&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt; &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;references /&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Nnjm2</name></author>
	</entry>
	<entry>
		<id>https://teaching.ncl.ac.uk/bms/wiki//index.php?title=Rough_endoplasmic_reticulum&amp;diff=2801&amp;oldid=prev</id>
		<title>100081905 at 20:43, 10 January 2011</title>
		<link rel="alternate" type="text/html" href="https://teaching.ncl.ac.uk/bms/wiki//index.php?title=Rough_endoplasmic_reticulum&amp;diff=2801&amp;oldid=prev"/>
		<updated>2011-01-10T20:43:10Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 20:43, 10 January 2011&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l1&quot;&gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Rough [[&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Endoplasmic_reticulum&lt;/del&gt;|endoplasmic reticulum]] is an organelle found in [[&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Eukaryotic_cells&lt;/del&gt;|eukaryotic cells]]. Its main function is to produce [[Proteins|proteins]]. &amp;lt;br&amp;gt;It is made up of cisternae, tubules and [[Vesicles|vesicles]]. The cisternae are made up of flattened membrane disks, which are involved in the modification of [[Proteins|proteins]]. They are held together by the [[Cytoskeleton|cytoskeleton]]. The rough [[&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Endoplasmic_reticulum&lt;/del&gt;|endoplasmic reticulum]] also contains a [[Perinuclear space|perinuclear space]], which is the space between the inner and outer [[Phospholipid|phospholipid]] membrane. The membrane is continuous to the [[Nuclear membrane|nuclear membrane]]. However, it isn’t continuous to the [[&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Golgi_apparatus&lt;/del&gt;|Golgi apparatus]]. [[Proteins|Proteins]] are transferred from the Rough endoplasmic reticulum to the [[Golgi apparatus|Golgi apparatus]] via membrane-bound vesicles. &amp;lt;br&amp;gt;The reason why it is rough endoplasmic reticulum is because of the [[Ribosomes|ribosomes]] attached to the [[&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Endoplasmic_reticulum&lt;/del&gt;|endoplasmic reticulum]]. These [[Ribosomes|ribosomes]] are constantly being attached and detached from the ER because they are not part of the stable [[Organelles|organelle]]. They attach when the [[Ribosomes|ribosome]] begins to synthesis a [[Proteins|protein]] which is going to be secreted ([[Secretory pathway|secretory pathway]]).&amp;lt;br&amp;gt;Rough [[&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Endoplasmic_reticulum&lt;/del&gt;|endoplasmic reticulum]] has a number of functions. One of the main functions of the rough [[&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Endoplasmic_reticulum&lt;/del&gt;|endoplasmic reticulum]] is to produce and process specific proteins. These are the exported through the [[Secretory pathway|secretory pathway]]. After they are exported via membrane [[Vesicles|vesicles]], they can be sent to the [[&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Golgi_apparatus&lt;/del&gt;|Golgi Apparatus]] to be further processed or to organelles. They can even be exported to outside the cell and into another part of the body. [[Ribosomes|Ribosomes]] also create proteins which are embedded into the rough endoplasmic reticulum for further processing (integral membrane proteins). Water soluble proteins are created too, which are exported through the membrane into the lumen. &amp;lt;br&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Rough [[&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Endoplasmic reticulum&lt;/ins&gt;|endoplasmic reticulum]] is an organelle found in [[&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Eukaryotic cells&lt;/ins&gt;|eukaryotic cells]]. Its main function is to produce [[Proteins|proteins]]. &amp;lt;br&amp;gt;It is made up of cisternae, tubules and [[Vesicles|vesicles]]. The cisternae are made up of flattened membrane disks, which are involved in the modification of [[Proteins|proteins]]. They are held together by the [[Cytoskeleton|cytoskeleton]]. The rough [[&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Endoplasmic reticulum&lt;/ins&gt;|endoplasmic reticulum]] also contains a [[Perinuclear space|perinuclear space]], which is the space between the inner and outer [[Phospholipid|phospholipid]] membrane. The membrane is continuous to the [[Nuclear membrane|nuclear membrane]]. However, it isn’t continuous to the [[&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Golgi apparatus&lt;/ins&gt;|Golgi apparatus]]. [[Proteins|Proteins]] are transferred from the Rough endoplasmic reticulum to the [[Golgi apparatus|Golgi apparatus]] via membrane-bound vesicles. &amp;lt;br&amp;gt;The reason why it is rough endoplasmic reticulum is because of the [[Ribosomes|ribosomes]] attached to the [[&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Endoplasmic reticulum&lt;/ins&gt;|endoplasmic reticulum]]. These [[Ribosomes|ribosomes]] are constantly being attached and detached from the ER because they are not part of the stable [[Organelles|organelle]]. They attach when the [[Ribosomes|ribosome]] begins to synthesis a [[Proteins|protein]] which is going to be secreted ([[Secretory pathway|secretory pathway]]).&amp;lt;br&amp;gt;Rough [[&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Endoplasmic reticulum&lt;/ins&gt;|endoplasmic reticulum]] has a number of functions. One of the main functions of the rough [[&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Endoplasmic reticulum&lt;/ins&gt;|endoplasmic reticulum]] is to produce and process specific proteins. These are the exported through the [[Secretory pathway|secretory pathway]]. After they are exported via membrane [[Vesicles|vesicles]], they can be sent to the [[&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Golgi apparatus&lt;/ins&gt;|Golgi Apparatus]] to be further processed or to organelles. They can even be exported to outside the cell and into another part of the body. [[Ribosomes|Ribosomes]] also create proteins which are embedded into the rough endoplasmic reticulum for further processing (integral membrane proteins). Water soluble proteins are created too, which are exported through the membrane into the lumen. &amp;lt;br&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt; &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;references /&amp;gt;[http://www.buzzle.com/articles/rough-endoplasmic-reticulum-function.html http://www.buzzle.com/articles/rough-endoplasmic-reticulum-function.html]&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>100081905</name></author>
	</entry>
	<entry>
		<id>https://teaching.ncl.ac.uk/bms/wiki//index.php?title=Rough_endoplasmic_reticulum&amp;diff=2134&amp;oldid=prev</id>
		<title>Nnjm2 at 19:42, 22 December 2010</title>
		<link rel="alternate" type="text/html" href="https://teaching.ncl.ac.uk/bms/wiki//index.php?title=Rough_endoplasmic_reticulum&amp;diff=2134&amp;oldid=prev"/>
		<updated>2010-12-22T19:42:12Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 19:42, 22 December 2010&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l1&quot;&gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Rough endoplasmic reticulum is an organelle found in eukaryotic cells. Its main function is to produce proteins. &amp;lt;br&amp;gt;It is made up of cisternae, tubules and vesicles. The cisternae are made up of flattened membrane disks, which are involved in the modification of proteins. They are held together by the cytoskeleton. The rough endoplasmic reticulum also contains a perinuclear space, which is the space between the inner and outer phospholipid membrane. The membrane is continuous to the nuclear membrane. However, it isn’t continuous to the Golgi apparatus. Proteins are transferred from the Rough endoplasmic reticulum to the Golgi apparatus via membrane-bound vesicles. &amp;lt;br&amp;gt;The reason why it is rough endoplasmic reticulum is because of the ribosomes attached to the endoplasmic reticulum. These ribosomes are constantly being attached and detached from the ER because they are not part of the stable organelle. They attach when the ribosome begins to synthesis a protein which is going to be secreted (secretory pathway).&amp;lt;br&amp;gt;Rough endoplasmic reticulum has a number of functions. One of the main functions of the rough endoplasmic reticulum is to produce and process specific proteins. These are the exported through the secretory pathway. After they are exported via membrane vesicles, they can be sent to the Golgi Apparatus to be further processed or to organelles. They can even be exported to outside the cell and into another part of the body. Ribosomes also create proteins which are embedded into the rough endoplasmic reticulum for further processing (integral membrane proteins). Water soluble proteins are created too, which are exported through the membrane into the lumen. &amp;lt;br&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Rough &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Endoplasmic_reticulum|&lt;/ins&gt;endoplasmic reticulum&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]] &lt;/ins&gt;is an organelle found in &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Eukaryotic_cells|&lt;/ins&gt;eukaryotic cells&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]]&lt;/ins&gt;. Its main function is to produce &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Proteins|&lt;/ins&gt;proteins&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]]&lt;/ins&gt;. &amp;lt;br&amp;gt;It is made up of cisternae, tubules and &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Vesicles|&lt;/ins&gt;vesicles&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]]&lt;/ins&gt;. The cisternae are made up of flattened membrane disks, which are involved in the modification of &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Proteins|&lt;/ins&gt;proteins&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]]&lt;/ins&gt;. They are held together by the &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Cytoskeleton|&lt;/ins&gt;cytoskeleton&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]]&lt;/ins&gt;. The rough &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Endoplasmic_reticulum|&lt;/ins&gt;endoplasmic reticulum&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]] &lt;/ins&gt;also contains a &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Perinuclear space|&lt;/ins&gt;perinuclear space&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]]&lt;/ins&gt;, which is the space between the inner and outer &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Phospholipid|&lt;/ins&gt;phospholipid&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]] &lt;/ins&gt;membrane. The membrane is continuous to the &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Nuclear membrane|&lt;/ins&gt;nuclear membrane&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]]&lt;/ins&gt;. However, it isn’t continuous to the &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Golgi_apparatus|&lt;/ins&gt;Golgi apparatus&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]]&lt;/ins&gt;. &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[&lt;/ins&gt;Proteins&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;|Proteins]] &lt;/ins&gt;are transferred from the Rough endoplasmic reticulum to the &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Golgi apparatus|&lt;/ins&gt;Golgi apparatus&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]] &lt;/ins&gt;via membrane-bound vesicles. &amp;lt;br&amp;gt;The reason why it is rough endoplasmic reticulum is because of the &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Ribosomes|&lt;/ins&gt;ribosomes&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]] &lt;/ins&gt;attached to the &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Endoplasmic_reticulum|&lt;/ins&gt;endoplasmic reticulum&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]]&lt;/ins&gt;. These &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Ribosomes|&lt;/ins&gt;ribosomes&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]] &lt;/ins&gt;are constantly being attached and detached from the ER because they are not part of the stable &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Organelles|&lt;/ins&gt;organelle&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]]&lt;/ins&gt;. They attach when the &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Ribosomes|&lt;/ins&gt;ribosome&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]] &lt;/ins&gt;begins to synthesis a &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Proteins|&lt;/ins&gt;protein&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]] &lt;/ins&gt;which is going to be secreted (&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Secretory pathway|&lt;/ins&gt;secretory pathway&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]]&lt;/ins&gt;).&amp;lt;br&amp;gt;Rough &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Endoplasmic_reticulum|&lt;/ins&gt;endoplasmic reticulum&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]] &lt;/ins&gt;has a number of functions. One of the main functions of the rough &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Endoplasmic_reticulum|&lt;/ins&gt;endoplasmic reticulum&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]] &lt;/ins&gt;is to produce and process specific proteins. These are the exported through the &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Secretory pathway|&lt;/ins&gt;secretory pathway&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]]&lt;/ins&gt;. After they are exported via membrane &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Vesicles|&lt;/ins&gt;vesicles&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]]&lt;/ins&gt;, they can be sent to the &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Golgi_apparatus|&lt;/ins&gt;Golgi Apparatus&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]] &lt;/ins&gt;to be further processed or to organelles. They can even be exported to outside the cell and into another part of the body. &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Ribosomes|&lt;/ins&gt;Ribosomes&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]] &lt;/ins&gt;also create proteins which are embedded into the rough endoplasmic reticulum for further processing (integral membrane proteins). Water soluble proteins are created too, which are exported through the membrane into the lumen. &amp;lt;br&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Nnjm2</name></author>
	</entry>
	<entry>
		<id>https://teaching.ncl.ac.uk/bms/wiki//index.php?title=Rough_endoplasmic_reticulum&amp;diff=2133&amp;oldid=prev</id>
		<title>100081905: Created page with &#039;Rough endoplasmic reticulum is an organelle found in eukaryotic cells. Its main function is to produce proteins. &lt;br&gt;It is made up of cisternae, tubules and vesicles. The cistern…&#039;</title>
		<link rel="alternate" type="text/html" href="https://teaching.ncl.ac.uk/bms/wiki//index.php?title=Rough_endoplasmic_reticulum&amp;diff=2133&amp;oldid=prev"/>
		<updated>2010-12-22T19:27:47Z</updated>

		<summary type="html">&lt;p&gt;Created page with &amp;#039;Rough endoplasmic reticulum is an organelle found in eukaryotic cells. Its main function is to produce proteins. &amp;lt;br&amp;gt;It is made up of cisternae, tubules and vesicles. The cistern…&amp;#039;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;Rough endoplasmic reticulum is an organelle found in eukaryotic cells. Its main function is to produce proteins. &amp;lt;br&amp;gt;It is made up of cisternae, tubules and vesicles. The cisternae are made up of flattened membrane disks, which are involved in the modification of proteins. They are held together by the cytoskeleton. The rough endoplasmic reticulum also contains a perinuclear space, which is the space between the inner and outer phospholipid membrane. The membrane is continuous to the nuclear membrane. However, it isn’t continuous to the Golgi apparatus. Proteins are transferred from the Rough endoplasmic reticulum to the Golgi apparatus via membrane-bound vesicles. &amp;lt;br&amp;gt;The reason why it is rough endoplasmic reticulum is because of the ribosomes attached to the endoplasmic reticulum. These ribosomes are constantly being attached and detached from the ER because they are not part of the stable organelle. They attach when the ribosome begins to synthesis a protein which is going to be secreted (secretory pathway).&amp;lt;br&amp;gt;Rough endoplasmic reticulum has a number of functions. One of the main functions of the rough endoplasmic reticulum is to produce and process specific proteins. These are the exported through the secretory pathway. After they are exported via membrane vesicles, they can be sent to the Golgi Apparatus to be further processed or to organelles. They can even be exported to outside the cell and into another part of the body. Ribosomes also create proteins which are embedded into the rough endoplasmic reticulum for further processing (integral membrane proteins). Water soluble proteins are created too, which are exported through the membrane into the lumen. &amp;lt;br&amp;gt;&lt;/div&gt;</summary>
		<author><name>100081905</name></author>
	</entry>
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