DNA topoisimerase: Difference between revisions

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 DNA topoiomerase plays an impotant role in breaking the phosophodiester bond by binding covalently onto the DNA backbone phosphate. It acst as a reversible nuclease. This whole process is a reversible one, whereby before the protein leaves, the phosophodiester bonds are re-made. There are two types of DNA topoisomerase, topoisomerase I and topoismerase II.  [1]

  1. Alberts, J. L. R. W., 2008. Molecular Biology of The Cell. 5th edition ed. Ney York: Garland Science.