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| DNA topoisomerase plays an impotant role in breaking the phosophodiester bond by binding covalently onto the DNA backbone phosphate. It acst as a reversible nuclease. This whole process is a reversible one, whereby before the protein leaves, the phosophodiester bonds are re-made. There are two types of DNA topoisomerase, topoisomerase I and topoismerase II.<br><br>
| | See [[DNA_topoisomerase|DNA topoisomerase ]] |
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| '''Reference:'''
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| 1. Alberts, BA, 2008. Molecular Biology of The Cell. 5th ed. New York: Garland Science.
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Latest revision as of 07:03, 12 October 2014