Polygenic: Difference between revisions

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A [[Disease|disease]] or trait that is described as being polygenic involves alleles of two or more&nbsp;[[Gene|genes]] - 'poly' coming from the Greek 'polus' meaning 'much' or 'polloi', meaning 'many'.<br>  
A [[Disease|disease]] or trait that is described as being polygenic involves alleles of two or more&nbsp;[[Gene|genes]] - 'poly' coming from the Greek 'polus' meaning 'much' or 'polloi', meaning 'many'.<br>  


A polygenic trait is a [[Phenotype|phenotype]] which is affected by multiple gene loci, for example height or eye colour. &nbsp;However, traits such as height can also be affected by [[environment|environment]], therefore they are described as [[Multifactorial|multifactorial]].  
A polygenic trait is a [[Phenotype|phenotype]] which is affected by multiple gene loci, for example height or eye colour. &nbsp;However, traits such as height can also be affected by [[Environment|environment]], therefore they are described as [[Multifactorial|multifactorial]]&nbsp;<ref>http://ghr.nlm.nih.gov/glossary=polygenic</ref><ref>Hartl, D and Ruvolo M, (2012) Genetics, Analysis of Genes and Genomes, Eighth Edition, Jones and Bartlett Learning, p663; 765</ref>.  


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<span style="font-size: 18px; font-weight: bold; line-height: 1.5em; background-color: initial;">References</span>


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<references />
 
1. &nbsp;http://ghr.nlm.nih.gov/glossary=polygenic
 
2. Hartl, D and Ruvolo M, (2012) Genetics, Analysis of Genes and Genomes, Eighth Edition, Jones and Bartlett Learning, p663; 765

Latest revision as of 07:37, 22 October 2014

A disease or trait that is described as being polygenic involves alleles of two or more genes - 'poly' coming from the Greek 'polus' meaning 'much' or 'polloi', meaning 'many'.

A polygenic trait is a phenotype which is affected by multiple gene loci, for example height or eye colour.  However, traits such as height can also be affected by environment, therefore they are described as multifactorial [1][2].

References

  1. http://ghr.nlm.nih.gov/glossary=polygenic
  2. Hartl, D and Ruvolo M, (2012) Genetics, Analysis of Genes and Genomes, Eighth Edition, Jones and Bartlett Learning, p663; 765