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Activator domains are modular proteins that stimulate [[Transcription|transcription]] via communicating with the transcription machinery "[[Pre-initation complex|pre-initation complex]]" (PIC).<ref>Lodish, H. et al.,2007.Molecular Cell Biology.Sixth Edition.New york:W.H.Freeman &amp;amp;amp; Co Ltd.</ref><br> | Activator domains are modular proteins that stimulate [[Transcription|transcription]] via communicating with the transcription machinery "[[Pre-initation complex|pre-initation complex]]" (PIC).<ref>Lodish, H. et al.,2007.Molecular Cell Biology.Sixth Edition.New york:W.H.Freeman &amp;amp;amp; Co Ltd.</ref><br> | ||
== Activators == | == Activators mechanisms == | ||
They work synergistically as it promotes binding of an additional activator. They bound to an enhancer to facilitate either the recruitment of RNA polymerase II to the promoter region or its elongation .<ref name="null">http://www.ncbi.nlm.nih.gov/pubmed/22180087</ref> | They work synergistically as it promotes binding of an additional activator. They bound to an enhancer to facilitate either the recruitment of RNA polymerase II to the promoter region or its elongation .<ref name="null">http://www.ncbi.nlm.nih.gov/pubmed/22180087</ref> | ||
=== References === | === References === | ||
<references />transcriptional activators and mechanisms ([http://www.ncbi.nlm.nih.gov/pubmed/22180087 http://www.ncbi.nlm.nih.gov/pubmed/22180087]) | <references />transcriptional activators and mechanisms ([http://www.ncbi.nlm.nih.gov/pubmed/22180087 http://www.ncbi.nlm.nih.gov/pubmed/22180087]) | ||
Revision as of 14:03, 19 October 2015
Activator domains are modular proteins that stimulate transcription via communicating with the transcription machinery "pre-initation complex" (PIC).[1]
Activators mechanisms
They work synergistically as it promotes binding of an additional activator. They bound to an enhancer to facilitate either the recruitment of RNA polymerase II to the promoter region or its elongation .[2]
References
- ↑ Lodish, H. et al.,2007.Molecular Cell Biology.Sixth Edition.New york:W.H.Freeman &amp;amp; Co Ltd.
- ↑ http://www.ncbi.nlm.nih.gov/pubmed/22180087
transcriptional activators and mechanisms (http://www.ncbi.nlm.nih.gov/pubmed/22180087)