Pleiotrophy: Difference between revisions
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Pleiotrophy is when a single [[Gene|gene]] influences multiple [[Phenotype|phenotypic]] traits that seem unrelated. An example of this is an [[Allele|allele]] ML whereby if a cat is a recessive [[Heterozygote|heterozygote]] then the cat doesn't grow a tail and is known as a manx cat. If the cat is a recessive [[Homozygote|homozygote]] they do not develop properly and is lethal. Therefore there is no true-breeding line of cats with the manx phenotype. The developmental basis of | Pleiotrophy is when a single [[Gene|gene]] influences multiple [[Phenotype|phenotypic]] traits that seem unrelated. An example of this is an [[Allele|allele]] ML whereby if a cat is a recessive [[Heterozygote|heterozygote]] then the cat doesn't grow a tail and is known as a manx cat. If the cat is a recessive [[Homozygote|homozygote]] they do not develop properly and it is lethal. Therefore there is no true-breeding line of cats with the manx phenotype. The developmental basis of pleiotrophy is unknown but the process by which pleiotrophy works is that the pleiotropic gene codes for a product that is has a function on different targets or is used by different cells. Antagonistic pleiotrophy is when the expression of a gene results in competing effects these can be detrimental or beneficial. | ||
Latest revision as of 19:46, 18 November 2015
Pleiotrophy is when a single gene influences multiple phenotypic traits that seem unrelated. An example of this is an allele ML whereby if a cat is a recessive heterozygote then the cat doesn't grow a tail and is known as a manx cat. If the cat is a recessive homozygote they do not develop properly and it is lethal. Therefore there is no true-breeding line of cats with the manx phenotype. The developmental basis of pleiotrophy is unknown but the process by which pleiotrophy works is that the pleiotropic gene codes for a product that is has a function on different targets or is used by different cells. Antagonistic pleiotrophy is when the expression of a gene results in competing effects these can be detrimental or beneficial.