Rna polymerases in eukaryotes: Difference between revisions
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Three types of RNA polymerases exist in eukaryotes- RNA polymerase I, RNA polymerase II and RNA polymerase III. These polymerases have different locations in the nucleus, respond to different inhibitors and are specific to different templates. See table 1 for details of these polymerases. | Three types of [[RNA|RNA]] polymerases exist in eukaryotes- [[RNA polymerase I|RNA polymerase I]], [[RNA polymerase II|RNA polymerase II]] and [[RNA polymerase III|RNA polymerase III]]. These polymerases have different locations in the [[Nucleus|nucleus]], respond to different inhibitors and are specific to different templates. See table 1 for details of these polymerases. | ||
Table 1: RNA Polymerases in Eukaryotes | Table 1: RNA Polymerases in Eukaryotes | ||
| Line 11: | Line 11: | ||
|- | |- | ||
| I | | I | ||
| Nucleolus | | [[Nucleus|Nucleolus]] | ||
| 18S, 5.8S,and 28S rRNA | | 18S, 5.8S,and 28S rRNA | ||
| Insensitive | | Insensitive | ||
|- | |- | ||
| II | | II | ||
| Nucleus | | [[Nucleus|Nucleus]] | ||
| mRNA, precursors and snRNA | | [[mRNA|mRNA]], precursors and snRNA | ||
| strongly inhibited | | strongly inhibited | ||
|- | |- | ||
| III | | III | ||
| Nucleus | | [[Nucleus|Nucleus]] | ||
| tRNA and 5S rRNA | | [[tRNA|tRNA]] and 5S rRNA | ||
| Inhibited by high concentrations | | Inhibited by high concentrations | ||
|} | |} | ||
''Pg 834, Biochemistry 6th Edition (2006)'' | ''Pg 834, Biochemistry 6th Edition (2006) <ref>Berg M. J., Tymoczko L. J., Stryer L., (2006) Biochemistry, 6th Edition New York: W. H Freeman</ref>'' | ||
References === | |||
<references /> | <references /> | ||
Revision as of 19:00, 23 November 2010
Three types of RNA polymerases exist in eukaryotes- RNA polymerase I, RNA polymerase II and RNA polymerase III. These polymerases have different locations in the nucleus, respond to different inhibitors and are specific to different templates. See table 1 for details of these polymerases.
Table 1: RNA Polymerases in Eukaryotes
| Type | Location | Cellular Transcripts | Effects of Alpha amanitin |
| I | Nucleolus | 18S, 5.8S,and 28S rRNA | Insensitive |
| II | Nucleus | mRNA, precursors and snRNA | strongly inhibited |
| III | Nucleus | tRNA and 5S rRNA | Inhibited by high concentrations |
Pg 834, Biochemistry 6th Edition (2006) [1] References ===
- ↑ Berg M. J., Tymoczko L. J., Stryer L., (2006) Biochemistry, 6th Edition New York: W. H Freeman