Tetanic contraction: Difference between revisions
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== '''Tetanic Muscle Contraction''' == | == '''Tetanic Muscle Contraction''' == | ||
Tetanic muscle contraction is a type of muscle contraction which occurs in skeletal muscles, resulting in a stronger prolonged contraction. Tetanic contraction occurs through summation of action potentials travelling into a muscle fibre<ref>1. . Muscle Contraction. http://michaeldmann.net/mann14.html (accessed 23/11/16).</ref>. As the frequency of the action potentials increases, the muscle has less time to relax and remove the Ca2+ ions in the sarcoplasm which initiated muscle contraction, through the binding to troponin, causing the myosin binding site to be revealed. Once a given frequency has been reached, the muscle fibre doesn't have time to remove all of the Ca2+ in the sarcoplasm before the next action potential, resulting in Ca2+ remaining in the sarcoplasm. As some Ca2+ remains in the sarcoplasm, when the next action potential arrives, more Ca2+ is released from the sarcoplasmic reticulum, resulting in a higher amount of Ca2+ in the sarcoplasm than in the first action potential. This results in a stronger contraction as more Ca2+ is present, so more myosin binding sites are unveiled, therefore more myosin-actin cross bridges can be formed. | Tetanic muscle contraction is a type of muscle contraction which occurs in skeletal muscles, resulting in a stronger prolonged contraction. Tetanic contraction occurs through summation of action potentials travelling into a muscle fibre<ref>1. . Muscle Contraction. http://michaeldmann.net/mann14.html (accessed 23/11/16).</ref>. As the frequency of the action potentials increases, the muscle has less time to relax and remove the Ca2+ ions in the sarcoplasm which initiated muscle contraction, through the binding to troponin, causing the myosin binding site to be revealed. Once a given frequency has been reached, the muscle fibre doesn't have time to remove all of the Ca2+ in the sarcoplasm before the next action potential, resulting in Ca2+ remaining in the sarcoplasm. As some Ca2+ remains in the sarcoplasm, when the next action potential arrives, more Ca2+ is released from the sarcoplasmic reticulum, resulting in a higher amount of Ca2+ in the sarcoplasm than in the first action potential. This results in a stronger contraction as more Ca2+ is present, so more myosin binding sites are unveiled, therefore more myosin-actin cross bridges can be formed<ref>2. . Ca2+ Regulation of Muscle Contraction. https://courses.washington.edu/conj/bess/muscle/calciumreg.html (accessed 23/11/16).</ref>. | ||
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=== '''References''' === | === '''References''' === | ||
'''1. . Muscle Contraction. http://michaeldmann.net/mann14.html (accessed 23/11/16).''' | '''1. . Muscle Contraction. http://michaeldmann.net/mann14.html (accessed 23/11/16).''' | ||
'''2. . Ca2+ Regulation of Muscle Contraction. https://courses.washington.edu/conj/bess/muscle/calciumreg.html (accessed 23/11/16).''' | |||
Revision as of 13:11, 23 November 2016
Tetanic Muscle Contraction
Tetanic muscle contraction is a type of muscle contraction which occurs in skeletal muscles, resulting in a stronger prolonged contraction. Tetanic contraction occurs through summation of action potentials travelling into a muscle fibre[1]. As the frequency of the action potentials increases, the muscle has less time to relax and remove the Ca2+ ions in the sarcoplasm which initiated muscle contraction, through the binding to troponin, causing the myosin binding site to be revealed. Once a given frequency has been reached, the muscle fibre doesn't have time to remove all of the Ca2+ in the sarcoplasm before the next action potential, resulting in Ca2+ remaining in the sarcoplasm. As some Ca2+ remains in the sarcoplasm, when the next action potential arrives, more Ca2+ is released from the sarcoplasmic reticulum, resulting in a higher amount of Ca2+ in the sarcoplasm than in the first action potential. This results in a stronger contraction as more Ca2+ is present, so more myosin binding sites are unveiled, therefore more myosin-actin cross bridges can be formed[2].
References
1. . Muscle Contraction. http://michaeldmann.net/mann14.html (accessed 23/11/16).
2. . Ca2+ Regulation of Muscle Contraction. https://courses.washington.edu/conj/bess/muscle/calciumreg.html (accessed 23/11/16).
- ↑ 1. . Muscle Contraction. http://michaeldmann.net/mann14.html (accessed 23/11/16).
- ↑ 2. . Ca2+ Regulation of Muscle Contraction. https://courses.washington.edu/conj/bess/muscle/calciumreg.html (accessed 23/11/16).