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PK8 influence on Cellular cAMP levels
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Revision as of 18:16, 24 November 2010

 PK8 Phosphorylates Phosphodiesterase 3D, which lowers cAMP concerntration in the cells through hydrolysis. PK8 also has a negative feedback effect on PKA, decreasing adenylyl cyclase activity as a result. This lowers cAMP levels even more.