Trisomy 8

 Trisomy 8 or Warkany Syndrome 2 is a chromosomal abmormality where three copies of the 8th chromosome are inherited. It can be a complete trisomy 8 that is lethal and causes early miscarriage or can be a mosaic Trisomy 8, where the person survives childhood and adulthood and bears a wide range of symptoms such as eye, kideny, heart, muscle and skeletal abnormalitis, distinctive facial characteristics such as widely spaces eyes, prominent forehead and skull. The Trisomy is the result of non-disjuncton during meioisis either durning or after fertilisation.