TATA promoter: Difference between revisions
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The TATA box is a common [[DNA transcription|DNA transcription]] [[Promoter|promoter]] found in [[Eukaryotes|eukaryotic]] [[Genes|genes]]. It has a [[Consensus sequence|consensus sequence]] of TATAAA<ref>Berg J M, Tymoczko J L, Gatto Jr G J, Stryer L. Biochemistry. 8th Ed, New York, NY: W. H. Freeman and Company. 2015 pg 122</ref>. The promoter is found upstream of the start [[Codon|codon]] ([[Methionine|methionine]] AUG) and is usually paired with an [[Initiator|initiator]] for efficient gene transcription. The TATA box's importance stems from its recognition by the [[TATA box binding protein|TATA box binding protein]] region of [[TFIID|TFIID]] one of the central components of the [[transcription initiation complex|transcription initiation complex]] with [[RNA polymerase II|RNA polymerase II]] and many other proteins<ref>Berg J M, Tymoczko J L, Gatto Jr G J, Stryer L. Biochemistry 8th Ed, New York, NY: W.H. Freeman and Company. 2015 pg 874-875</ref>. | |||
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Latest revision as of 18:50, 23 October 2017
The TATA box is a common DNA transcription promoter found in eukaryotic genes. It has a consensus sequence of TATAAA[1]. The promoter is found upstream of the start codon (methionine AUG) and is usually paired with an initiator for efficient gene transcription. The TATA box's importance stems from its recognition by the TATA box binding protein region of TFIID one of the central components of the transcription initiation complex with RNA polymerase II and many other proteins[2].