Presynaptic neurone: Difference between revisions
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When an [[Action potential|action potential arrives]] at the [[Axon terminal|axon terminal]] of the presynaptic membrane, Ca2+ ion channels open, allowing the ions to move into the cell down their [[Concentration Gradient|concentration gradient]]. This in turn causes the neurotransmitter containing [[Vesicles|vesicles]] to translocate and fuse to the [[Presynaptic membrane|presynaptic membrane]]. The neurotransmitter diffuses across the synapse and starts a new action potential in the post synaptic neurone. | When an [[Action potential|action potential arrives]] at the [[Axon terminal|axon terminal]] of the presynaptic membrane, Ca2+ ion channels open, allowing the ions to move into the cell down their [[Concentration Gradient|concentration gradient]]. This in turn causes the neurotransmitter containing [[Vesicles|vesicles]] to translocate and fuse to the [[Presynaptic membrane|presynaptic membrane]]. The neurotransmitter diffuses across the synapse and starts a new action potential in the post synaptic neurone. | ||
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<u>Reference</u> | |||
Purves D, Augustine GJ, Fitzpatrick D, et al., editors. Neuroscience. 2nd edition. Sunderland (MA): Sinauer Associates; 2001. Excitatory and Inhibitory Postsynaptic Potentials. Available from: https://www.ncbi.nlm.nih.gov/books/NBK11117/<br>accessed 17/11/17<br> | |||
Revision as of 18:32, 17 November 2017
The presynaptic neurone is the neurone that releases neurotransmitter, across the synapse, to the post synaptic neurone.
When an action potential arrives at the axon terminal of the presynaptic membrane, Ca2+ ion channels open, allowing the ions to move into the cell down their concentration gradient. This in turn causes the neurotransmitter containing vesicles to translocate and fuse to the presynaptic membrane. The neurotransmitter diffuses across the synapse and starts a new action potential in the post synaptic neurone.
Reference
Purves D, Augustine GJ, Fitzpatrick D, et al., editors. Neuroscience. 2nd edition. Sunderland (MA): Sinauer Associates; 2001. Excitatory and Inhibitory Postsynaptic Potentials. Available from: https://www.ncbi.nlm.nih.gov/books/NBK11117/
accessed 17/11/17