Composition of prokaryotic ribosome: Difference between revisions
Created page with "An E.coli ribosome is a <u>ribonucleoprotein</u> assembly with a mass of about 2500kDa. Ribosomes are abundant (10% of total protein and 80% RNA). A ribosome (70S) can be dissoci..." |
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An E.coli ribosome is a | An ''[[E. coli|E. coli]]'' ribosome is a ribonucleoprotein assembly with a mass of about 2500 kDa. Ribosomes are abundant (10% of total [[protein|protein]] and 80% [[RNA|RNA]]). A ribosome (70S) can be dissociated into large subunit (50S) and a small subunit (30S). The formation of 70S initiation complex is the rate-limiting step in [[protein synthesis|protein synthesis]]. These subunits can be further split into their consituent proteins and RNAs. | ||
The '''30S subunit''' contains 21 different proteins and a 16S RNA molecule. 16S subunit pairs with purine-rich region called Shine-Dalgano sequence. The number of base pairs linking mRNA and 16S rRNA ranges from 3 to 9. In addition, AUG codon pairs with initiator tRNA. | The '''30S subunit''' contains 21 different proteins and a 16S RNA molecule. 16S subunit pairs with purine-rich region called [[Shine_dalgarno|Shine-Dalgano sequence]]. The number of base pairs linking [[MRNA|mRNA]] and 16S [[RRNA|rRNA]] ranges from 3 to 9. In addition, AUG [[codon|codon]] pairs with initiator [[tRNA|tRNA]]. | ||
The '''50S subunit''' conains 34 different proteins and two RNA molecules, a 23S and a 5S species. 23S subunit is important in the formation of peptide bond. | The '''50S subunit''' conains 34 different proteins and two RNA [[molecules|molecules]], a 23S and a 5S species. 23S subunit is important in the formation of [[peptide bond|peptide bond]]. | ||
S= Svedberg unit (measure sedimentation rate in centrifuge and thus size) | S = [[Svedberg unit|Svedberg unit]] (measure sedimentation rate in [[centrifuge|centrifuge]] and thus size)<ref>Rhodes, Carl Douglas, et al. Student companion to accompany Biochemistry, eighth edition. W.H. Freeman and Company, a Macmillan Education Company, 2015. (pg 902)</ref>.<br> | ||
=== References === | |||
<references /><br> | |||
Latest revision as of 08:13, 5 December 2017
An E. coli ribosome is a ribonucleoprotein assembly with a mass of about 2500 kDa. Ribosomes are abundant (10% of total protein and 80% RNA). A ribosome (70S) can be dissociated into large subunit (50S) and a small subunit (30S). The formation of 70S initiation complex is the rate-limiting step in protein synthesis. These subunits can be further split into their consituent proteins and RNAs.
The 30S subunit contains 21 different proteins and a 16S RNA molecule. 16S subunit pairs with purine-rich region called Shine-Dalgano sequence. The number of base pairs linking mRNA and 16S rRNA ranges from 3 to 9. In addition, AUG codon pairs with initiator tRNA.
The 50S subunit conains 34 different proteins and two RNA molecules, a 23S and a 5S species. 23S subunit is important in the formation of peptide bond.
S = Svedberg unit (measure sedimentation rate in centrifuge and thus size)[1].
References
- ↑ Rhodes, Carl Douglas, et al. Student companion to accompany Biochemistry, eighth edition. W.H. Freeman and Company, a Macmillan Education Company, 2015. (pg 902)