Bronchoconstriction: Difference between revisions
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Bronchoconstriction is the constriction of airways in the lungs, caused by smooth muscle contraction in the lungs decreasing their diameter. Both the [ | Bronchoconstriction is the constriction of airways in the [[lungs|lungs]], caused by [[smooth muscle contraction|smooth muscle contraction]] in the lungs decreasing their diameter. Both the [[autonomic nervous system|autonomic nervous system]] and chemical mediators are responsible for regulating this process<ref>Larson Jr, Jaffe, Practical Anaesthetic Management, The Art of Anaesthesiology, 1st Edition, Springer International Publishing, 2017, 52 - 53</ref>. | ||
There are drugs that can cause bronchoconstriction such as: muscarinic agonists (e.g. pilocarpine), β2 noradrenergic receptor antagonists (e.g. propranolol), A1 noradrenergic receptor antagonists (e.g. prazosin) and H1 agonists (e.g. histamine). | There are drugs that can cause bronchoconstriction such as: [[muscarinic agonists|muscarinic agonists]] (e.g. [[pilocarpine|pilocarpine]]), [[β2 noradrenergic receptor antagonists|β2 noradrenergic receptor antagonists]] (e.g. [[propranolol|propranolol]]), [[A1 noradrenergic receptor antagonists|A1 noradrenergic receptor antagonists]] (e.g. [[prazosin|prazosin]]) and [[H1 agonists|H1 agonists]] (e.g. [[histamine|histamine]]). | ||
[ | [[Asthma|Asthma]], a common ailment in which airways become irritated and bronchoconstriction causes difficulty breathing, is treated by drugs that inhibit bronchoconstriction and allow [[bronchodilation|bronchodilation]] to occur. | ||
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Latest revision as of 16:57, 23 October 2018
Bronchoconstriction is the constriction of airways in the lungs, caused by smooth muscle contraction in the lungs decreasing their diameter. Both the autonomic nervous system and chemical mediators are responsible for regulating this process[1].
There are drugs that can cause bronchoconstriction such as: muscarinic agonists (e.g. pilocarpine), β2 noradrenergic receptor antagonists (e.g. propranolol), A1 noradrenergic receptor antagonists (e.g. prazosin) and H1 agonists (e.g. histamine).
Asthma, a common ailment in which airways become irritated and bronchoconstriction causes difficulty breathing, is treated by drugs that inhibit bronchoconstriction and allow bronchodilation to occur.
References
- ↑ Larson Jr, Jaffe, Practical Anaesthetic Management, The Art of Anaesthesiology, 1st Edition, Springer International Publishing, 2017, 52 - 53