Exosome: Difference between revisions
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The exosome is the main 3' to 5' [[Exonuclease]] in the cell. It is involved in the RNA turnover and processing in the cell<ref>https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-016-0268-z</ref>.<br> | |||
The exosome is a multisubunit complex. The subunits mean that there is multiple [[Nuclease|nuclease]] activites. [[Rrp44|Rrp44]] is used in a large number of diverse RNA processing and degradation events in eukaryotes<ref>https://www.ncbi.nlm.nih.gov/pubmed/22833611</ref>. | The exosome is a multisubunit complex. The subunits mean that there is multiple [[Nuclease|nuclease]] activites. [[Rrp44|Rrp44]] is used in a large number of diverse RNA processing and degradation events in eukaryotes<ref>https://www.ncbi.nlm.nih.gov/pubmed/22833611</ref>. | ||
[[Rrp6|Rrp6]] is another "nuclear-specific catalytic component of the RNA exosome complex" | [[Rrp6|Rrp6]] is another "nuclear-specific catalytic component of the RNA exosome complex"<ref>https://www.uniprot.org/uniprot/Q12149</ref> and is another subunit which provides nuclease activity. The rest of the subunits function in RNA binding/unwinding. | ||
=== References === | |||
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Latest revision as of 16:40, 25 October 2018
The exosome is the main 3' to 5' Exonuclease in the cell. It is involved in the RNA turnover and processing in the cell[1].
The exosome is a multisubunit complex. The subunits mean that there is multiple nuclease activites. Rrp44 is used in a large number of diverse RNA processing and degradation events in eukaryotes[2].
Rrp6 is another "nuclear-specific catalytic component of the RNA exosome complex"[3] and is another subunit which provides nuclease activity. The rest of the subunits function in RNA binding/unwinding.
References