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Proinsulin is the precursor to insulin. It is synthesised by the pancreas within the cells which make up the the islets of Langerhans. Proinsulin is formed from pre-proinsulin when the signal peptide is cleaved off, and successively mature insulin is formed when the C peptide is cleaved via endoproteases from proinsulin.<ref>https://en.wikipedia.org/wiki/Proinsulin</ref> | Proinsulin is the precursor to insulin. It is synthesised by the pancreas within the cells which make up the the islets of Langerhans. Proinsulin is formed from pre-proinsulin when the signal peptide is cleaved off, and successively mature insulin is formed when the C peptide is cleaved via endoproteases from proinsulin.[[Islets_of_Langerhans|javascript:void(0);/*1544024822580*/]]<ref>https://en.wikipedia.org/wiki/Proinsulin</ref> | ||
Without proinsulin insulin would not be able to be genrated which would cause a wide range of disorders and illneses. | Without proinsulin, insulin would not be able to be genrated which would cause a wide range of disorders and illneses within humans. | ||
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Revision as of 15:47, 5 December 2018
Proinsulin is the precursor to insulin. It is synthesised by the pancreas within the cells which make up the the islets of Langerhans. Proinsulin is formed from pre-proinsulin when the signal peptide is cleaved off, and successively mature insulin is formed when the C peptide is cleaved via endoproteases from proinsulin.javascript:void(0);/*1544024822580*/[1]
Without proinsulin, insulin would not be able to be genrated which would cause a wide range of disorders and illneses within humans.