Proinsulin: Difference between revisions
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Proinsulin is the precursor to insulin. It is synthesised by the pancreas within the cells which make up the the islets of Langerhans. Proinsulin is formed from pre-proinsulin when the signal peptide is cleaved off, and successively mature insulin is formed when the C peptide is cleaved via endoproteases from proinsulin. | Proinsulin is the precursor to insulin. It is synthesised by the pancreas within the cells which make up the the islets of Langerhans. Proinsulin is formed from pre-proinsulin when the signal peptide is cleaved off, and successively mature insulin is formed when the C peptide is cleaved via endoproteases from proinsulin.<ref>https://en.wikipedia.org/wiki/Proinsulin</ref> | ||
Without proinsulin, insulin would not be able to be genrated which would cause a wide range of disorders and illneses within humans. | Without proinsulin, insulin would not be able to be genrated which would cause a wide range of disorders and illneses within humans. | ||
Revision as of 15:47, 5 December 2018
Proinsulin is the precursor to insulin. It is synthesised by the pancreas within the cells which make up the the islets of Langerhans. Proinsulin is formed from pre-proinsulin when the signal peptide is cleaved off, and successively mature insulin is formed when the C peptide is cleaved via endoproteases from proinsulin.[1]
Without proinsulin, insulin would not be able to be genrated which would cause a wide range of disorders and illneses within humans.