Disjunction: Difference between revisions
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Disjunction is a process which sees [[Homologous chromosomes|homologous chromosomes]], that are lined up along the [[Equatorial plate|equatorial plate]], gradually drawn towards opposite poles of a [[Cell|cell]], by structures known as [[Spindle fibres|spindle fibres]]. The process of disjunction occurs in both [[Mitosis|mitosis]] and [[Meiosis|meiosis]] cell division and is associated with the [[Anaphase|anaphase]] stage. If two sister [[Chromatids|chromatids]] do not separate correctly during the process, [[Nondisjunction]] occurs. This then leads to an incorrect number of [[Chromosome|chromosomes]], in one of the two dividing cells, and this is known as [[Aneuploidy]]. This can lead to disorders | Disjunction is a process which sees [[Homologous chromosomes|homologous chromosomes]], that are lined up along the [[Equatorial plate|equatorial plate]], gradually drawn towards opposite poles of a [[Cell|cell]], by structures known as [[Spindle fibres|spindle fibres]]. The process of disjunction occurs in both [[Mitosis|mitosis]] and [[Meiosis|meiosis]] cell division and is associated with the [[Anaphase|anaphase]] stage. If two sister [[Chromatids|chromatids]] do not separate correctly during the process, [[Nondisjunction]] occurs. This then leads to an incorrect number of [[Chromosome|chromosomes]], in one of the two dividing cells, and this is known as [[Aneuploidy]]. This can lead to disorders such as a trisomy 21 (downs syndrome), trisomy 18 (Edwards syndrome), trisomy 13 (Patau's Syndrome). | ||
Revision as of 10:05, 6 December 2018
Disjunction is a process which sees homologous chromosomes, that are lined up along the equatorial plate, gradually drawn towards opposite poles of a cell, by structures known as spindle fibres. The process of disjunction occurs in both mitosis and meiosis cell division and is associated with the anaphase stage. If two sister chromatids do not separate correctly during the process, Nondisjunction occurs. This then leads to an incorrect number of chromosomes, in one of the two dividing cells, and this is known as Aneuploidy. This can lead to disorders such as a trisomy 21 (downs syndrome), trisomy 18 (Edwards syndrome), trisomy 13 (Patau's Syndrome).