Glycagon: Difference between revisions
Glucagon is synthesized in alpha cells of the islets in the pancreas and increases blood glucose levels when low blood sugar concentration. |
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Revision as of 07:55, 11 January 2011
- Structure
Glucagon is a kind of peptide hormone with 29 amino acids in a linear structure. Glucagon is produced originally as a formation of proglucagon in the pancreas, which is then converted to glucagon as a functional state in alpha cells of the islets. Cite error: Invalid <ref> tag; name cannot be a simple integer. Use a descriptive title
- Function
The primary role of glucagon played in the body is increasing the blood glucose concentrations, which is the opposite function of insulin, secreted from beta cells of the isletsCite error: Invalid <ref> tag; name cannot be a simple integer. Use a descriptive title. To be specific, glucagon raises the blood sugar levels through the breakdown of the glycogen in the liver when the concentration of the blood glucose is low. This process is called glycogenolysis, which is decomposition of glycogen into glucose. Cite error: Invalid <ref> tag; name cannot be a simple integer. Use a descriptive title Another function of glucagon is activating gluconeogenesis, which convert non-hexose, for instance, amino acids, to glucose also for increasing the blood sugar levelsCite error: Invalid <ref> tag; name cannot be a simple integer. Use a descriptive title.
- Disease
Glucagonomas is a result of excessive seglucagon excretion, which causes some harm effects,for example, skin lesions.Cite error: Invalid <ref> tag; name cannot be a simple integer. Use a descriptive title