G-proteins: Difference between revisions

Revision as of 11:12, 1 November 2010

Guanine nucleotide binding protein that binds GTP when activated, which it hydrolyses to GDP. The active form of the protein can interact with a number of down stream effectors such as adenylyl cyclase (producing cAMP from ATP), and phospholipase C (PLC).

The G-proteins can be divided in to two families - the heterotrimeric G-proteins and the small or mono-meric G-proteins.

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	[[Guanine nucleotide\|Guanine nucleotide]] binding [[~~protein~~\|protein]] that binds [[GTP\|GTP]] when activated, which it hydrolyses to [[GDP\|GDP]].  The active form of the [[~~protein~~\|protein]] can interact with a number of down stream effectors such as [[~~adenylyl~~ cyclase\|adenylyl cyclase]] (producing [[~~cAMP~~\|cAMP]] from [[ATP\|ATP]]), and [[~~phospholipase~~ C\|phospholipase C]] ([[PLC\|PLC]]).		[[Guanine nucleotide\|Guanine nucleotide]] binding [[Protein\|protein]] that binds [[GTP\|GTP]] when activated, which it hydrolyses to [[GDP\|GDP]].  The active form of the [[Protein\|protein]] can interact with a number of down stream effectors such as [[Adenylyl cyclase\|adenylyl cyclase]] (producing [[CAMP\|cAMP]] from [[ATP\|ATP]]), and [[Phospholipase C\|phospholipase C]] ([[PLC\|PLC]]).

	The G-proteins can be divided in to two families - the [[~~heterotrimeric~~ G-proteins\|heterotrimeric G-proteins]] and the small or [[~~mono~~-meric G-proteins\|mono-meric G-proteins]].		The [[G-proteins\|G-proteins]] can be divided in to two families - the [[Heterotrimeric G-proteins\|heterotrimeric G-proteins]] and the small or [[Mono-meric G-proteins\|mono-meric G-proteins]].