Zellweger Syndrome: Difference between revisions
Jump to navigation
Jump to search
Created page with "Zellweger Syndrome is an inherited disease where the lack of proteins in peroxisomes leads to peroxisomal deficiency. This can be caused by a mutation in..." |
(No difference)
|
Revision as of 00:22, 15 November 2011
Zellweger Syndrome is an inherited disease where the lack of proteins in peroxisomes leads to peroxisomal deficiency. This can be caused by a mutation in gene encoding peroxon Pex2 (related to protein import) which will lead to severe abnormalities in major organs (brain, liver & kidneys) and can result in death.[1] It is the most severe of the 4 peroxisome biogenesis disorders (PBD) and there is no cure for it. Also. there are only limited treatments available as the metabolic and neurological pathways involved, are affected during fetal development.[2]
- ↑ Alberts et al.,2008, Molecular biology of the cell, Fifth ed., Page 723, New York, Garland science
- ↑ http://www.ninds.nih.gov/disorders/zellweger/zellweger.htm