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| A disulphide bridge can also be called a [[Disulphide bond|disulphide bond]]. It is the name of the [[Covalent bond|covalent bond]] that is formed when two thiol groups, SH groups, undergo [[Oxidation|oxidation]] and a bond forms between the two [[Sulphur|sulphur]] atoms. In the formation of this type of bond, two [[Protons|protons]] and two [[Electron|electron]]s are produced as biproducts.
| | See [[Disulphide_bond|disulphide bond ]] |
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| Disulphide bonds are often present in [[Tertiary Protein Structure|tertiary protein structure]] between [[Cysteine|cysteine]] residues, as they help to stabilise the protein. The S-S bonds are formed as part of the folding of the protein into its final 3D structure in the [[Endoplasmic reticulum]]<ref>http://www.ncbi.nlm.nih.gov/pubmed/10754564</ref>.
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| The disulphide bonds only occur on the extracellular domains of a protein, as in the [[Cytosol]] (a reducing environment) the bonds become unstable and break.
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| = References =
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| <references />
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Revision as of 21:31, 22 November 2011