G-proteins: Difference between revisions

From The School of Biomedical Sciences Wiki
Jump to navigation Jump to search
Nnjm2 (talk | contribs)
No edit summary
No edit summary
Line 2: Line 2:


The [[G-proteins|G-proteins]] can be divided in to two families - the [[Heterotrimeric G-proteins|heterotrimeric&nbsp;G-proteins]] and the small or [[Mono-meric G-proteins|mono-meric G-proteins]].<br>
The [[G-proteins|G-proteins]] can be divided in to two families - the [[Heterotrimeric G-proteins|heterotrimeric&nbsp;G-proteins]] and the small or [[Mono-meric G-proteins|mono-meric G-proteins]].<br>
G-protein coupled receptors ([[GPCR|GPCR]]) upon binding of [[stimulus|stimulus]] activates G-protein.

Revision as of 13:11, 12 November 2010

Guanine nucleotide binding protein that binds GTP when activated, which it hydrolyses to GDP.  The active form of the protein can interact with a number of down stream effectors such as adenylyl cyclase (producing cAMP from ATP), and phospholipase C (PLC).

The G-proteins can be divided in to two families - the heterotrimeric G-proteins and the small or mono-meric G-proteins.

G-protein coupled receptors (GPCR) upon binding of stimulus activates G-protein.