P-glycoprotein: Difference between revisions

From The School of Biomedical Sciences Wiki
Jump to navigation Jump to search
Nnjm2 (talk | contribs)
No edit summary
Line 1: Line 1:
The P-glycoprotein is part of the [[ABC_Superfamily|ABC superfamily]] and is involved in drug efflux and therefore multi-drug resistance.
The P-glycoprotein is part of the [[ABC Superfamily|ABC superfamily]]&nbsp;and is involved in drug efflux and therefore multi-drug resistance. The [[ABC_Superfamily|ABC superfamily ]]can be divided into seven subfamilies, P-glycoprotein being a member of the subfamily [[MDR/TAP|MDR/TAP]]. <ref>Reversion of resistance to immunosuppressive agents in three patients with psoriatic arthritis by cyclosporine A. Andrea Picchianti Diamanti. 2010. PubMed.</ref>P-glycoprotein can be inhibited by [[cyclosporine A|cyclosporine A]] and [[verapamil|verapamil]].
 
 
 
=== References ===
 
&nbsp;<references />

Revision as of 13:35, 12 November 2010

The P-glycoprotein is part of the ABC superfamily and is involved in drug efflux and therefore multi-drug resistance. The ABC superfamily can be divided into seven subfamilies, P-glycoprotein being a member of the subfamily MDR/TAP. [1]P-glycoprotein can be inhibited by cyclosporine A and verapamil.


References

 

  1. Reversion of resistance to immunosuppressive agents in three patients with psoriatic arthritis by cyclosporine A. Andrea Picchianti Diamanti. 2010. PubMed.