Monomeric G-protein: Difference between revisions

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&nbsp; A monomeric G-protein ( also known as small G protein or small GTPases, is the umbrella term for a family of signal transducing proteins. These comprise of: Rab, Arf, Ras, Ran and Rho, which are also vital in the growth of cells, as well as cell transport, motility, cytokinesis and cell differentiation.<ref>Berg et al., (2006) Biochemistry, 6th edition, New York. Pages 432</ref>&nbsp;Monomeric G proteins comprise of two forms, 1.) an 'inactive' form in which the monomeric G-protein is bound to GDP ( guanosine diphosphate), and 2.) the 'active' &nbsp;form in which the Monomeric G-protein is bound to GTP ( guanosine triphosphate). Notably, Monomeric&nbsp;G-proteins are small,( ranging around 20-25 Kd,) compared with larger types of G protein like Heterotrimeric proteins ( which are typically 30-35 Kd).<ref>Berg et al., (2006) Biochemistry, 6th edition, New York. Pages 433</ref> <br> <br> <br> <br> References:&nbsp;  
&nbsp; A monomeric G-protein ( also known as small G protein or small GTPases, is the umbrella term for a family of signal transducing proteins. These comprise of: Rab, Arf, Ras, Ran and Rho, which are also vital in the growth of cells, as well as cell transport, motility, cytokinesis and cell differentiation.<ref>Berg et al., (2006) Biochemistry, 6th edition, New York. Pages 432</ref>&nbsp;Monomeric G proteins comprise of two forms, 1.) an 'inactive' form in which the monomeric G-protein is bound to GDP ( guanosine diphosphate), and 2.) the 'active' &nbsp;form in which the Monomeric G-protein is bound to GTP ( guanosine triphosphate). Notably, Monomeric&nbsp;G-proteins are small,( ranging around 20-25 Kd,) compared with larger types of G protein like Heterotrimeric proteins ( which are typically 30-35 Kd).<ref>Berg et al., (2006) Biochemistry, 6th edition, New York. Pages 433</ref> <br> <br> <br> <br> References:&nbsp;  


<references />Berg et al., (2006) Biochemistry, 6th edition, New York. Pages 432
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Revision as of 19:41, 13 November 2012

  A monomeric G-protein ( also known as small G protein or small GTPases, is the umbrella term for a family of signal transducing proteins. These comprise of: Rab, Arf, Ras, Ran and Rho, which are also vital in the growth of cells, as well as cell transport, motility, cytokinesis and cell differentiation.[1] Monomeric G proteins comprise of two forms, 1.) an 'inactive' form in which the monomeric G-protein is bound to GDP ( guanosine diphosphate), and 2.) the 'active'  form in which the Monomeric G-protein is bound to GTP ( guanosine triphosphate). Notably, Monomeric G-proteins are small,( ranging around 20-25 Kd,) compared with larger types of G protein like Heterotrimeric proteins ( which are typically 30-35 Kd).[2]



References: 

  1. Berg et al., (2006) Biochemistry, 6th edition, New York. Pages 432
  2. Berg et al., (2006) Biochemistry, 6th edition, New York. Pages 433