GEF: Difference between revisions
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GEF, also known as Sos, is a protein linked with the [[Ras pathway|RAS pathway]]. It opens up the nucleotide-binding pocket of [[Ras|Ras]]. This releases [[GDP|GDP]] and allows [[GTP|GTP]] to attach to Ras, thus activating it <ref>Berg J, Stryer L, Tymoczko J. (2011) Biochemistry, 7th Edition. International Edition, Basingstoke: Palgrave Macmillan. Page 431.</ref>. | |||
=== References === | |||
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Latest revision as of 07:03, 25 November 2012
GEF, also known as Sos, is a protein linked with the RAS pathway. It opens up the nucleotide-binding pocket of Ras. This releases GDP and allows GTP to attach to Ras, thus activating it [1].
References
- ↑ Berg J, Stryer L, Tymoczko J. (2011) Biochemistry, 7th Edition. International Edition, Basingstoke: Palgrave Macmillan. Page 431.