Supercoiled: Difference between revisions
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Created page with "When the circular DNA of the SV40 virus is isolated and separated from its associated protein, the DNA duplex is underwound and assumes the supercoiled configuration.[1] <br> ..." |
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Localised unwinding of a circular DNA molecule, which occurs during DNA replication, induces torsional stress into the remaining portion of the molecule because the ends of the strands are not free to rotate. As a result, the DNA molecule twists back on itself, like a twisted rubber band, forming supercoils.[1] | |||
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References | References | ||
1. ^Lodish,H.,Berk,A.,Kaiser,C.A.,Krieger,M.,Bretscher,A.,Ploegh,H., and Amon,A. (2013) ''Molecular Cell Biology, '' | 1. ^ Lodish,H.,Berk,A.,Kaiser,C.A.,Krieger,M.,Bretscher,A.,Ploegh,H., and Amon,A. (2013) ''Molecular Cell Biology, '' | ||
Revision as of 21:26, 23 October 2013
Localised unwinding of a circular DNA molecule, which occurs during DNA replication, induces torsional stress into the remaining portion of the molecule because the ends of the strands are not free to rotate. As a result, the DNA molecule twists back on itself, like a twisted rubber band, forming supercoils.[1]
References
1. ^ Lodish,H.,Berk,A.,Kaiser,C.A.,Krieger,M.,Bretscher,A.,Ploegh,H., and Amon,A. (2013) Molecular Cell Biology,