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| Intermediate filaments are a component of [[Cytoskeleton|cytoskeleton]]. They are around 10 nm, and are present in both [[Cytoplasm|cytoplasm]] and [[Nucleus|nucleus]]. These help provide the [[cell|cell]] with mechanical strength and are also strong and stable due to the packing of coiled [[fibrillar protein|fibrillar protein]]s in a rope like structure. The different types of intermediate filaments that can be found in the [[Cytoplasm|cytoplasm]] of different cells can be used in tumour characterisation techniques within the health and research industries. Different categories of cytoplasmic intermediate filaments are found in; the [[Epithelial cells|epithelia]] as keratins, the connective tissue as [[vimentin|vimentin]], and the nerve cells as [[neurofilaments|neurofilaments]]. The main type of intermediate filaments found in the [[Nucleus|nucleus]] are called [[Nuclear lamins|nuclear lamins]] and are present in all nucleated cells, nuclear lamins lie just underneath the inner face of the [[Nuclear envelope|nuclear envelope]] and provide mechanical strength to the [[Nucleus|nucleus]] as well as providing attachment sites for the [[Chromosome|chromosomes]], but do break down during [[Mitosis|mitosis cell]] division <ref>Alberts,B., Johnson,A., Lewis, J., Raff, M., Roberts, K., and Watson, J. (2007). Molecular Biology of the Cell, 5th edition. Garland.</ref>.
| | See [[Intermediate_filament|Intermediate filament]] |
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| === Reference ===
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Latest revision as of 09:47, 23 November 2013