From The School of Biomedical Sciences Wiki
Jump to navigation
Jump to search
|
|
| Line 1: |
Line 1: |
| Intermediate filaments are a component of [[Cytoskeleton|cytoskeleton]]. They are around 10 nm, and are present in both [[Cytoplasm|cytoplasm]] and [[Nucleus|nucleus]]. These help provide the [[Cell|cell]] with mechanical strength and are also strong and stable due to the packing of coiled [[Fibrillar protein|fibrillar proteins]] in a rope like structure. The different types of intermediate filaments that can be found in the [[Cytoplasm|cytoplasm]] of different cells can be used in tumour characterisation techniques within the health and research industries. Different categories of cytoplasmic intermediate filaments are found in; the [[Epithelial cells|epithelia]] as keratins, the connective tissue as [[Vimentin|vimentin]], and the nerve cells as [[Neurofilaments|neurofilaments]]. The main type of intermediate filaments found in the [[Nucleus|nucleus]] are called [[Nuclear lamins|nuclear lamins]] and are present in all nucleated cells, nuclear lamins lie just underneath the inner face of the [[Nuclear envelope|nuclear envelope]] and provide mechanical strength to the [[Nucleus|nucleus]] as well as providing attachment sites for the [[Chromosome|chromosomes]], but do break down during [[Mitosis|mitosis cell]] division <ref>Alberts,B., Johnson,A., Lewis, J., Raff, M., Roberts, K., and Watson, J. (2007). Molecular Biology of the Cell, 5th edition. Garland.</ref>.<br>
| | See [[Intermediate_filament|Intermediate filament]] |
| | |
| === Reference ===
| |
| | |
| <references />
| |
| | |
| <br>
| |
Latest revision as of 09:47, 23 November 2013